Abstract
We propose a macroscopic description of some inhibitors of oxidative phosphorylation based on a simple modification of the phenomenological coefficients appearing in the constitutive equations of linear irreversible thermodynamics. In this theoretical model, we consider protonophores, some ATPase inactivators and some electron-chain inhibitors, and we provide quantitative expressions for their consequences on the protonmotive force, oxidation flux and phosphorylation flux as well as on heat generation. © 1985 Academic Press Inc. (London) Ltd.
Original language | English |
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Pages (from-to) | 471-488 |
Journal | Journal of Theoretical Biology |
Volume | 117 |
DOIs | |
Publication status | Published - 7 Dec 1985 |