A simple nonequilibrium thermodynamic description of some inhibitors of oxidative phosphorylation

David Jou; Fernando Ferrer

doi:https://doi.org/10.1016/S0022-5193(85)80155-7

A simple nonequilibrium thermodynamic description of some inhibitors of oxidative phosphorylation

David Jou, Fernando Ferrer

Department of Physics

Research output: Contribution to journal › Article › Research › peer-review

13 Citations (Scopus)

Abstract

We propose a macroscopic description of some inhibitors of oxidative phosphorylation based on a simple modification of the phenomenological coefficients appearing in the constitutive equations of linear irreversible thermodynamics. In this theoretical model, we consider protonophores, some ATPase inactivators and some electron-chain inhibitors, and we provide quantitative expressions for their consequences on the protonmotive force, oxidation flux and phosphorylation flux as well as on heat generation. © 1985 Academic Press Inc. (London) Ltd.

Original language	English
Pages (from-to)	471-488
Journal	Journal of Theoretical Biology
Volume	117
DOIs	https://doi.org/10.1016/S0022-5193(85)80155-7
Publication status	Published - 7 Dec 1985

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title = "A simple nonequilibrium thermodynamic description of some inhibitors of oxidative phosphorylation",

abstract = "We propose a macroscopic description of some inhibitors of oxidative phosphorylation based on a simple modification of the phenomenological coefficients appearing in the constitutive equations of linear irreversible thermodynamics. In this theoretical model, we consider protonophores, some ATPase inactivators and some electron-chain inhibitors, and we provide quantitative expressions for their consequences on the protonmotive force, oxidation flux and phosphorylation flux as well as on heat generation. {\textcopyright} 1985 Academic Press Inc. (London) Ltd.",

author = "David Jou and Fernando Ferrer",

year = "1985",

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T1 - A simple nonequilibrium thermodynamic description of some inhibitors of oxidative phosphorylation

AU - Jou, David

AU - Ferrer, Fernando

PY - 1985/12/7

Y1 - 1985/12/7

N2 - We propose a macroscopic description of some inhibitors of oxidative phosphorylation based on a simple modification of the phenomenological coefficients appearing in the constitutive equations of linear irreversible thermodynamics. In this theoretical model, we consider protonophores, some ATPase inactivators and some electron-chain inhibitors, and we provide quantitative expressions for their consequences on the protonmotive force, oxidation flux and phosphorylation flux as well as on heat generation. © 1985 Academic Press Inc. (London) Ltd.

AB - We propose a macroscopic description of some inhibitors of oxidative phosphorylation based on a simple modification of the phenomenological coefficients appearing in the constitutive equations of linear irreversible thermodynamics. In this theoretical model, we consider protonophores, some ATPase inactivators and some electron-chain inhibitors, and we provide quantitative expressions for their consequences on the protonmotive force, oxidation flux and phosphorylation flux as well as on heat generation. © 1985 Academic Press Inc. (London) Ltd.

U2 - https://doi.org/10.1016/S0022-5193(85)80155-7

DO - https://doi.org/10.1016/S0022-5193(85)80155-7

M3 - Article

VL - 117

SP - 471

EP - 488

JO - Journal of Theoretical Biology

JF - Journal of Theoretical Biology

SN - 0022-5193

ER -