A Quick Reference on Anion Gap and Strong Ion Gap

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    4 Citations (Scopus)


    © 2016 Elsevier Inc. Metabolic acid-base disorders are common in emergency and critically ill patients. Clinicians may have difficulty recognizing their presence when multiple acid-base derangements are present in a single patient simultaneously. The anion gap and the strong ion gap concepts are useful calculations to identify the components of complex metabolic acid-base associated to the presence of unmeasured anions. This article presents their definition, normal values, indications, limitations, and guidelines for interpretation of changes in the clinical setting.
    Original languageEnglish
    Pages (from-to)191-196
    JournalVeterinary Clinics of North America - Small Animal Practice
    Issue number2
    Publication statusPublished - 1 Mar 2017


    • Acid-base
    • Anion gap
    • Metabolic acidosis
    • Small animals
    • Strong ion gap
    • Unmeasured anions


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