A new platelet parameter, the mean platelet component, can demonstrate abnormal platelet function and structure in myelodysplasia

D. R. Brummitt; H. F. Barker; N. Pujol-Moix

doi:10.1046/j.1365-2257.2003.00488.x

A new platelet parameter, the mean platelet component, can demonstrate abnormal platelet function and structure in myelodysplasia

D. R. Brummitt, H. F. Barker, N. Pujol-Moix

Department of Medicine

Research output: Contribution to journal › Article › Research › peer-review

11 Citations (Scopus)

Abstract

The mean platelet component (MPC) is a new platelet parameter generated by the Bayer ADVIA™ 120 full blood count analyser as part of the routine complete blood count (CBC) test cycle. We report a case of myelodysplasia with bleeding complications and abnormal template bleeding time in whom low mean platelet component parameters were associated with partial platelet granule deficiency, demonstrated by transmission electron microscopy. We suggest that the mean platelet component is an inexpensive and rapid test to screen for platelet dysfunction related to ultrastructural abnormalities in myelodysplasia.

Original language	English
Pages (from-to)	59-62
Journal	Clinical and Laboratory Haematology
Volume	25
Issue number	1
DOIs	https://doi.org/10.1046/j.1365-2257.2003.00488.x
Publication status	Published - 1 Feb 2003

Keywords

ADVIA™ 120
Mean platelet component
Myelodysplasia
Platelet function
Platelet transmission electron microscopy

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title = "A new platelet parameter, the mean platelet component, can demonstrate abnormal platelet function and structure in myelodysplasia",

abstract = "The mean platelet component (MPC) is a new platelet parameter generated by the Bayer ADVIA{\texttrademark} 120 full blood count analyser as part of the routine complete blood count (CBC) test cycle. We report a case of myelodysplasia with bleeding complications and abnormal template bleeding time in whom low mean platelet component parameters were associated with partial platelet granule deficiency, demonstrated by transmission electron microscopy. We suggest that the mean platelet component is an inexpensive and rapid test to screen for platelet dysfunction related to ultrastructural abnormalities in myelodysplasia.",

keywords = "ADVIA{\texttrademark} 120, Mean platelet component, Myelodysplasia, Platelet function, Platelet transmission electron microscopy",

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AU - Brummitt, D. R.

AU - Barker, H. F.

AU - Pujol-Moix, N.

PY - 2003/2/1

Y1 - 2003/2/1

N2 - The mean platelet component (MPC) is a new platelet parameter generated by the Bayer ADVIA™ 120 full blood count analyser as part of the routine complete blood count (CBC) test cycle. We report a case of myelodysplasia with bleeding complications and abnormal template bleeding time in whom low mean platelet component parameters were associated with partial platelet granule deficiency, demonstrated by transmission electron microscopy. We suggest that the mean platelet component is an inexpensive and rapid test to screen for platelet dysfunction related to ultrastructural abnormalities in myelodysplasia.

AB - The mean platelet component (MPC) is a new platelet parameter generated by the Bayer ADVIA™ 120 full blood count analyser as part of the routine complete blood count (CBC) test cycle. We report a case of myelodysplasia with bleeding complications and abnormal template bleeding time in whom low mean platelet component parameters were associated with partial platelet granule deficiency, demonstrated by transmission electron microscopy. We suggest that the mean platelet component is an inexpensive and rapid test to screen for platelet dysfunction related to ultrastructural abnormalities in myelodysplasia.

KW - ADVIA™ 120

KW - Mean platelet component

KW - Myelodysplasia

KW - Platelet function

KW - Platelet transmission electron microscopy

U2 - 10.1046/j.1365-2257.2003.00488.x

DO - 10.1046/j.1365-2257.2003.00488.x

M3 - Article

VL - 25

SP - 59

EP - 62

JO - International Journal of Laboratory Hematology

JF - International Journal of Laboratory Hematology

SN - 1751-5521

IS - 1

ER -