A morphometric ultrastructural study of the nucleus of cerebellar granule cells

J. P. Hervás; M. T. Berciano; I. Silos; M. Lafarga

doi:10.1159/000146972

A morphometric ultrastructural study of the nucleus of cerebellar granule cells

J. P. Hervás, M. T. Berciano, I. Silos, M. Lafarga

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Abstract

A quantitative approach to the nuclear infrastructure of cerebellar granule cells is described here. The study was made using conventional electron microscopy from cerebellar cortices of adult rats by means of a semiautomatic image analyzer. The basic observation is that the nuclei of mature granule cells constitute a homogeneous population in terms of morphometric and stereologic data; in fact, the volume density of condensed chromatin within the nuclei remains practically constant in all nuclear sections. These results seem to indicate the existence of a cell-specific nuclear morphometric phenotype which might be considered as an effective criterion for the typification of this cellular lineage. © 1990 S. Karger AG, Basel.

Original language	English
Pages (from-to)	5-10
Journal	Cells Tissues Organs
Volume	139
Issue number	1
DOIs	https://doi.org/10.1159/000146972
Publication status	Published - 1 Jan 1990

Keywords

Cell nucleus
Cell phenotype
Cerebellum
Granule cells
Morphometry
Neurons

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title = "A morphometric ultrastructural study of the nucleus of cerebellar granule cells",

abstract = "A quantitative approach to the nuclear infrastructure of cerebellar granule cells is described here. The study was made using conventional electron microscopy from cerebellar cortices of adult rats by means of a semiautomatic image analyzer. The basic observation is that the nuclei of mature granule cells constitute a homogeneous population in terms of morphometric and stereologic data; in fact, the volume density of condensed chromatin within the nuclei remains practically constant in all nuclear sections. These results seem to indicate the existence of a cell-specific nuclear morphometric phenotype which might be considered as an effective criterion for the typification of this cellular lineage. {\textcopyright} 1990 S. Karger AG, Basel.",

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AU - Hervás, J. P.

AU - Berciano, M. T.

AU - Silos, I.

AU - Lafarga, M.

PY - 1990/1/1

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N2 - A quantitative approach to the nuclear infrastructure of cerebellar granule cells is described here. The study was made using conventional electron microscopy from cerebellar cortices of adult rats by means of a semiautomatic image analyzer. The basic observation is that the nuclei of mature granule cells constitute a homogeneous population in terms of morphometric and stereologic data; in fact, the volume density of condensed chromatin within the nuclei remains practically constant in all nuclear sections. These results seem to indicate the existence of a cell-specific nuclear morphometric phenotype which might be considered as an effective criterion for the typification of this cellular lineage. © 1990 S. Karger AG, Basel.

AB - A quantitative approach to the nuclear infrastructure of cerebellar granule cells is described here. The study was made using conventional electron microscopy from cerebellar cortices of adult rats by means of a semiautomatic image analyzer. The basic observation is that the nuclei of mature granule cells constitute a homogeneous population in terms of morphometric and stereologic data; in fact, the volume density of condensed chromatin within the nuclei remains practically constant in all nuclear sections. These results seem to indicate the existence of a cell-specific nuclear morphometric phenotype which might be considered as an effective criterion for the typification of this cellular lineage. © 1990 S. Karger AG, Basel.

KW - Cell nucleus

KW - Cell phenotype

KW - Cerebellum

KW - Granule cells

KW - Morphometry

KW - Neurons

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SP - 5

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A morphometric ultrastructural study of the nucleus of cerebellar granule cells

Abstract

Keywords

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