A quantitative approach to the nuclear infrastructure of cerebellar granule cells is described here. The study was made using conventional electron microscopy from cerebellar cortices of adult rats by means of a semiautomatic image analyzer. The basic observation is that the nuclei of mature granule cells constitute a homogeneous population in terms of morphometric and stereologic data; in fact, the volume density of condensed chromatin within the nuclei remains practically constant in all nuclear sections. These results seem to indicate the existence of a cell-specific nuclear morphometric phenotype which might be considered as an effective criterion for the typification of this cellular lineage. © 1990 S. Karger AG, Basel.
|Journal||Cells Tissues Organs|
|Publication status||Published - 1 Jan 1990|
- Cell nucleus
- Cell phenotype
- Granule cells