A morphometric ultrastructural study of the nucleus of cerebellar granule cells

J. P. Hervás, M. T. Berciano, I. Silos, M. Lafarga

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    Abstract

    A quantitative approach to the nuclear infrastructure of cerebellar granule cells is described here. The study was made using conventional electron microscopy from cerebellar cortices of adult rats by means of a semiautomatic image analyzer. The basic observation is that the nuclei of mature granule cells constitute a homogeneous population in terms of morphometric and stereologic data; in fact, the volume density of condensed chromatin within the nuclei remains practically constant in all nuclear sections. These results seem to indicate the existence of a cell-specific nuclear morphometric phenotype which might be considered as an effective criterion for the typification of this cellular lineage. © 1990 S. Karger AG, Basel.
    Original languageEnglish
    Pages (from-to)5-10
    JournalCells Tissues Organs
    Volume139
    Issue number1
    DOIs
    Publication statusPublished - 1 Jan 1990

    Keywords

    • Cell nucleus
    • Cell phenotype
    • Cerebellum
    • Granule cells
    • Morphometry
    • Neurons

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