A model for continuous production of thermally induced recombinant proteins

R. Cubarsí, A. Benito, M. Vidal, J. Cairó, A. Villaverde

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

General conditions for continuous expression of heterologous genes from PL promoter in two fermenters connected in series have been established. The induction time of the bacterial cells is calculated as a function of the retention time in the inducing reactor. Using this model, it is possible to adapt fermentation parameters to the particular behaviour of any specific recombinant clone. © 1991 Kluwer Academic Publishers.
Original languageEnglish
Pages (from-to)249-254
JournalBiotechnology Letters
Volume13
DOIs
Publication statusPublished - 1 Apr 1991

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