Abstract
The present study describes the effects of a commercially available genetically engineered chimeric vaccine against porcine circovirus type 2 (PCV2) on clinical, pathological and virological features in three multi-site farms suffering from postweaning multisystemic wasting syndrome (PMWS). The vaccine product was able to reduce clinical signs, PCV2 viral load in lymphoid organs and/or sera, and overall mortality in nurseries and fattening units. This is the first time in which is shown that a PCV2 vaccine is able to decrease specifically PMWS-associated mortality. Another novelty of this study is the assessment of PMWS-like histological lesions in a large number of vaccinated and non-vaccinated pigs under field conditions. © 2009 Elsevier Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 7313-7321 |
Journal | Vaccine |
Volume | 27 |
Issue number | 52 |
DOIs | |
Publication status | Published - 9 Dec 2009 |
Keywords
- Porcine circovirus type 2 (PCV2)
- Postweaning multisystemic wasting syndrome (PMWS)
- Vaccine