A carbon nanotube PVC based matrix modified with glutaraldehyde suitable for biosensor applications

Briza Pérez-López, Joan Sola, Salvador Alegret, Arben Merkoçi

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Abstract

Carbon nanotubes (CNTs) are offering a great promise for developing electrochemical sensors. Distinctive properties of CNTs such as a high surface area, ability to accumulate analyte, minimization of surface fouling and electrocatalytic activity are very attractive for electrochemical sensing. The electrochemical study of a glassy carbon (GC) electrode coated with a matrix based in multiwall carbon nanotubes (MWCNTs), tetrahydrofuran (THF) mixed with poly(vinyl chloride) (PVC) and with a glutaraldehyde (GA) solution (MWCNTs-TPG/GC), for β-Nicotinamide adenine dinucleotide (NADH) detection is discussed in this work using cyclic voltammetry (CV) and chronoamperometry. The used CNTs matrix promotes better the electron transfer of NADH minimizing the fouling effect. The obtained results show remarkable electrochemical and mechanical advantages of MWCNTs-TPG/GC electrode compared to bare glassy carbon electrode with a great promise for future amperometric biosensors applications. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.
Original languageEnglish
Pages (from-to)603-610
JournalElectroanalysis
Volume20
Issue number6
DOIs
Publication statusPublished - 1 Mar 2008

Keywords

  • Electrochemical sensing
  • Glassy carbon electrode
  • Multiwall carbon nanotubes
  • NADH
  • Polymeric matrix

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