3,4-Methylenedioxymethamphetamine (MDMA) intoxication in an infant chronically exposed to cocaine

Oscar Garcia-Algar; Nuria Lopez; Mariona Bonet; Manuela Pellegrini; Emilia Marchei; Simona Pichini

doi:10.1097/01.ftd.0000166041.97524.50

3,4-Methylenedioxymethamphetamine (MDMA) intoxication in an infant chronically exposed to cocaine

Oscar Garcia-Algar, Nuria Lopez, Mariona Bonet, Manuela Pellegrini, Emilia Marchei, Simona Pichini

Department of Paediatrics, Obstetrics and Gynaecology and Preventive Medicine and Public Health

Research output: Contribution to journal › Article › Research › peer-review

27 Citations (Scopus)

Abstract

Accidental ingestion of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) was detected in an infant admitted at the Pediatric Emergency Department by drug testing in urine. Concentrations of MDMA and its principal metabolite 4-hydroxy-3-methoxymethamphetamine (HMMA) in the infant's hydrolyzed urine were 11.7 mg/L and 34.4 mg/L, respectively. Apparent febrile convulsions and cardiovascular side effects resolved within 1 day after treatment with benzodiazepines. Chronic exposure to cocaine was evidenced by segmental hair analysis. Continuous maternal denial of the presence of any drug in the household made diagnosis of accidental ingestion of MDMA and chronic exposure to cocaine problematic. Periodic clinical and laboratory follow-ups were requested to check eventual long-term effects of exposure to illicit drugs and discontinuation of the child from exposure to dangerous environments. Copyright © 2005 by Lippincott Williams & Wilkins.

Original language	English
Pages (from-to)	409-411
Journal	Therapeutic Drug Monitoring
Volume	27
Issue number	4
DOIs	https://doi.org/10.1097/01.ftd.0000166041.97524.50
Publication status	Published - 1 Aug 2005

Keywords

Chronic exposure
Cocaine
Ecstasy
Infant
Intoxication

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10.1097/01.ftd.0000166041.97524.50

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title = "3,4-Methylenedioxymethamphetamine (MDMA) intoxication in an infant chronically exposed to cocaine",

abstract = "Accidental ingestion of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) was detected in an infant admitted at the Pediatric Emergency Department by drug testing in urine. Concentrations of MDMA and its principal metabolite 4-hydroxy-3-methoxymethamphetamine (HMMA) in the infant's hydrolyzed urine were 11.7 mg/L and 34.4 mg/L, respectively. Apparent febrile convulsions and cardiovascular side effects resolved within 1 day after treatment with benzodiazepines. Chronic exposure to cocaine was evidenced by segmental hair analysis. Continuous maternal denial of the presence of any drug in the household made diagnosis of accidental ingestion of MDMA and chronic exposure to cocaine problematic. Periodic clinical and laboratory follow-ups were requested to check eventual long-term effects of exposure to illicit drugs and discontinuation of the child from exposure to dangerous environments. Copyright {\textcopyright} 2005 by Lippincott Williams & Wilkins.",

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author = "Oscar Garcia-Algar and Nuria Lopez and Mariona Bonet and Manuela Pellegrini and Emilia Marchei and Simona Pichini",

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TY - JOUR

T1 - 3,4-Methylenedioxymethamphetamine (MDMA) intoxication in an infant chronically exposed to cocaine

AU - Garcia-Algar, Oscar

AU - Lopez, Nuria

AU - Bonet, Mariona

AU - Pellegrini, Manuela

AU - Marchei, Emilia

AU - Pichini, Simona

PY - 2005/8/1

Y1 - 2005/8/1

N2 - Accidental ingestion of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) was detected in an infant admitted at the Pediatric Emergency Department by drug testing in urine. Concentrations of MDMA and its principal metabolite 4-hydroxy-3-methoxymethamphetamine (HMMA) in the infant's hydrolyzed urine were 11.7 mg/L and 34.4 mg/L, respectively. Apparent febrile convulsions and cardiovascular side effects resolved within 1 day after treatment with benzodiazepines. Chronic exposure to cocaine was evidenced by segmental hair analysis. Continuous maternal denial of the presence of any drug in the household made diagnosis of accidental ingestion of MDMA and chronic exposure to cocaine problematic. Periodic clinical and laboratory follow-ups were requested to check eventual long-term effects of exposure to illicit drugs and discontinuation of the child from exposure to dangerous environments. Copyright © 2005 by Lippincott Williams & Wilkins.

AB - Accidental ingestion of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) was detected in an infant admitted at the Pediatric Emergency Department by drug testing in urine. Concentrations of MDMA and its principal metabolite 4-hydroxy-3-methoxymethamphetamine (HMMA) in the infant's hydrolyzed urine were 11.7 mg/L and 34.4 mg/L, respectively. Apparent febrile convulsions and cardiovascular side effects resolved within 1 day after treatment with benzodiazepines. Chronic exposure to cocaine was evidenced by segmental hair analysis. Continuous maternal denial of the presence of any drug in the household made diagnosis of accidental ingestion of MDMA and chronic exposure to cocaine problematic. Periodic clinical and laboratory follow-ups were requested to check eventual long-term effects of exposure to illicit drugs and discontinuation of the child from exposure to dangerous environments. Copyright © 2005 by Lippincott Williams & Wilkins.

KW - Chronic exposure

KW - Cocaine

KW - Ecstasy

KW - Infant

KW - Intoxication

U2 - 10.1097/01.ftd.0000166041.97524.50

DO - 10.1097/01.ftd.0000166041.97524.50

M3 - Article

SN - 0163-4356

VL - 27

SP - 409

EP - 411

JO - Therapeutic Drug Monitoring

JF - Therapeutic Drug Monitoring

IS - 4

ER -

3,4-Methylenedioxymethamphetamine (MDMA) intoxication in an infant chronically exposed to cocaine

Abstract

Keywords

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