The general object for this project is the study iof chemical processes of aromatic or heteroaromatic compounds where single electron transfer steps are involved, with the aim of learning ro control them and in that way achieving new mild, selective and ecologically compatible synthetic methods and new materials. The differnent points to be studied will be: 1) The importance of electrostatic effects in the evolution of radical anion intermediates. Topollogicallu controlled coulombic interactions. We will follow our studies on the reductive fragmentation of arrly ethers and we plant to start studies on the effects of electrostatic interactions on the nucleophilic aromatic fotosubstitution-SET reactions. 2) A radical mechanism in the thermal nucleophilic aromatic sustitution reaction (SNAr) of nitroaromatic derivatives? We plant to studuy the influence of traces of oxygen in the outcome of SNAr reactions and to develop a mechanistic rationale in agreement with the observed results. 3) Nucleophilic aromatic substitution for hydrogen. Study of the scope of this photochemical reaction promoted by fluoride anion, recently discovered in our Group, and developement of a electrochemical version. 4) Supramolecular photochemistry and electrochemistry in cyclodextrin complexes. We will use the inclusion in cyclodextrins in the solid state as closed vessels where to carry out fundamental mechanistic studies. Also, we plan to study the altering of the normal reactivity by electrostatic interaction in the inclusion complexes. 5) Fundamental studies on the electrochemical oxidation of amines on the surface of a carbon electrode. Our aim is to achieve regular monolayers in the electrode surface with applicability as new materials and in the study of the reactivity of charged intermediates in the presence of electric fields.
|Effective start/end date||1/10/97 → 1/10/00|
- Dirección General de Enseñanza Superior e Investigación Científica: €90,151.82