The objective of the present project is the development, manufacture and validation of biosensores based on the technology of microsystems and the magnetic particle use. These biosensores will be integrated in compact systems of simple use, that allow their use in-situ (portable systems) and which they do not require of personnel specialized for his handling. These systems of biological detection have an ample rank of potential applications, that go from the test of potable water, clinical foods and analyses. Three principles of detection will be approached: ISFETs in which the magnetic particles are used like support of the reagents; Biomechanic sensors, that detect magnetic particles due to the deflection that takes place in a cantilever one of silicon when they are put under a magnetic field; Bio-L, sensors based on the measurement of the changes of inductance due to the magnetic particle presence. In these two last cases, the magnetic particles are used as marking of the reagents and present/display advantages like greater sensitivity, minor inespecífica answer, and low cost for applications one-time. The devices to develop in the project have as final mission the conception and design of systems of automated analyses of easy mobility, under consumption and cost reduced for the dtección of biological molecules. The objective of the project is not as much to develop a concrete application, but the design, the manufacture and validation of a prototype that is adaptable of simple form to different applications.
|Effective start/end date||7/11/01 → 7/11/04|
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