RM estructural y funcional en pacientes con dolor crònico tipo fibromialgia. Correlatos con las dimensiones básicas de la personalidad

  • Deus Yela, Joan (Principal Investigator)
  • López Solà, Marina (Scholar)
  • Gomà-i-Freixanet , Montserrat (Investigator)
  • Juanola Roura, F. Javier (Investigator)
  • Lopez-Araquistan Serrano, Laura (Investigator)
  • Perich Alsina, Javier (Investigator)
  • Pujol Nuez, Jesús (Investigator)

Project Details

Description

\b OBJECTIVES\b0 . To study by means of functional magnetic resonance (RMf) the pattern of cerebral answer to the pain during the administration of a constant mechanical pressure and of low intensity, that does not cause pain in normal conditions, in patients clinically diagnosed of fibromyalgia (FM) wuith respect to a group of health control. To compare the morphology of the neuroanatomics structures, by means of the volumetric RM, implied in cerebral answer to the pain of the patientswith diagnoses of FM with respect to the subject of health controls and their relation with the basic dimensions of the personality and styles of facing.
\b METHODOLOGY\b0 . \b Design\b0 . Study marry-control. \b Sample\b0 They will includy in the study a group of 40 patients who will fulfil the clinical diarnose of Fibromyalgia according to criteria diagnoses of the American Coolege of Rheumatology (ACR). 40 healthy volunteers will be used like control group, to wich it will mate by age and years fron study to the patients with Fibromyalgia diagnosis. \b Scope of Study\b0 . Service of psychiatry and rheumatilogy of the University Hospital of Bellvitge and Institut d'Alta Tecnologia (IAT) of Barceloan of Parc de Recerca Biomédica de Barcelona (PRBB). \b Variables\b0 . NEUROFUNCTIONALS Variables will be obtained, that will constitute the main variables of study ( the activated intensity and number of voxels in answer to the pain during the administration of a mechanical pressure) and NEUROSTRUCTURALS (dimensions of specific cerebral regions from the voletric RM or 3D). Previous to the acomplishment of the RMf, CLINICAL and PERSONALITY variables will be obtained by means of psychometrics tests will constitute the secondary variables of the study. \b Statistical Analysis\b0 . The analysis and processing of the functional sequences will be carried out with the computer science program FuncTool (exploratory analysis) and the SPM-2 program (...)
StatusFinished
Effective start/end date1/12/0730/11/10

Funding

  • Ministerio de Educación y Ciencia: €129,470.00

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