RI services to promote deep digitalization of Industrial Biotechnology - towards smart biomanufacturing

Project Details


Industrial Biotechnology (IB) is a Key Enabling Technology for the circular bio-economy, industrial renewal and European manufacturing autonomy. Its development forms a vital part of EU’s strategy to become climate neutral in 2050. For IB to become a major manufacturing technology, it must widen its use of advanced digital technologies. These will improve R&D efficiency, reducing time-to-market and costs. Moreover, for manufacturing, advanced digital technologies will drive distributed, autonomous and highly adaptable production systems. To support digitalization of IB, BIOINDUSTRY 4.0 will create new services delivered by European research infrastructures (RI). These services will address several challenges, focusing on the acceleration of bio-process development pipelines. Drawing on the complementary skills of its consortium, BIOINDUSTRY 4.0 will develop data-driven approaches, exploiting AI to empower novel decision support systems and digital twins, the latter being to better design bio-processes and enable their real-time online control. To complete these services, BIOINDUSTRY 4.0 will also develop data and metadata standards to generate high quality, interoperable multi-scale bio-process data, the technical basis for trusted data networks and process analytical devices to provide real-time online monitoring of bio-processes. Once deployed, these RI services will provide Users with access to cutting-edge technologies that can be used singly or in an integrated way, covering whole R&D pipelines. Integrated services will be delivered by a distributed RI, conferring Europe with a unique R&D test-bed for bio-process development and a competitive advantage with respect to global competition. To succeed, BIOINDUSTRY 4.0 brings together 6 EU RIs, 1 global company, 2 innovative EU SMEs and several research teams around an ambitious 4-year workplan that will be implemented in consultation with IB stakeholders, using a co-design strategy to specify goals.
Short titleBIOINDUSTRY 4.0
Effective start/end date1/01/2331/12/26

Collaborative partners

  • Universitat Autònoma de Barcelona (UAB)
  • French National Research Institute for Agriculture, Food and Environment (INRAE) (lead)
  • Athina-Erevnitiko Kentro Kainotomias Stis Technologies Tis Pliroforias, Ton Epikoinonion Kai Tis Gnosis (ATHENA RC)
  • Association Industries Et Agro-Ressources (B4C)
  • National Research Council of Italy
  • Leibniz-Institut Dsmz-Deutsche Sammlung Von Mikroorganismen Und Zellkulturen Gmbh (DSMZ)
  • University Koblenz-Landau (Campus Landau)
  • INRA Transfert
  • National Institute of Applied Sciences - Toulouse centre (INSA)
  • Royal Netherlands Academy of Arts and Sciences
  • LifeGlimmer GmbH
  • National Technical University of Athens
  • Rheinisch Westfälischen Technische Hochshule Aachen
  • Timegate Instruments Oy (TIMEGATE)
  • University of Valencia (UV)
  • VITO - Flemish Institute for Technological Research (Vlaamse Instelling voor Technologisch Onderzoek)
  • Teknologian tutkimuskeskus vtt oy
  • University of Wageningen
  • Biofaction KG (BFC)


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