Paracentric inversions have been by far the most frequent type of cytological change during the evolution of the genus "Drosophila". Using molecular techniques and theoretical models we address in this proposal some of the crucial and unsolved questions cencerning the origin and evolution of chromosomal inversions such as the genetic consequences and non-random distribution of inversions breakpoints, the age of the inversions or the rate of gene flow between choromosome arrangements. We will study the species "D.buzzatii" which belongs to the repleta species gruop and is polymorphic for inversions on the second and fourth chromosomes. The main research goals are: 1) To extend the molecular map already available of the "D. buzzatii second chromosome, in particular with regard to the chromosome regions near the inversion breakpoints. 2) To clone and sequence the breakpoints of the polymorp
|Effective start/end date||11/09/96 → 11/09/99|
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.