Optimació de les tècniques de caracterització genètica en el diagnòstic preimplantacional humà

  • Santalo Pedro, Josep (Principal Investigator)
  • Barrios Sanromà, Leonardo (Investigator)
  • Egozcue Cuixart, Josep (Investigator)
  • Ponsà Fontanals, Montserrat (Investigator)
  • Vidal Dominguez, Francesca (Investigator)
  • Grossmann Camps, Mark (Scholar)

    Project Details


    Study objective: development and setting of the genetic characterization techniques in preimplantation diagnosis. Design: a first developing phase in an animal model (mouse), followed by its application in human preembryos. Setting: it depend on the phase of the study considered. The first phase concerning the development in the mouse model will be carried on mainly in the Unit of Cell Biology of the Department of Cell Biology and Physiology of the Autonomous University of Barcelona. The second one that implies the clinical application of the results will be performed using the human preembryos from the "in vitro" fertilization (IVF) program of the Department of Obstetrics and Gynaecology of the Clinical Hospital of Barcelona. Patients: preembryos obtained by IVF from couples carrying some genetic disease with a high risk to be transmitted to the offspring (>25%) will be considered. Inte
    Effective start/end date1/01/9531/12/97


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