Chromosomal rearrangements that contribute to human patologic processes, also contribute to speciation processes during evolution and can appear as a result of clastogenic agents. The chromosomal points affected are not random but are hot points liable to suffer damage. There is eviden that many sites afected by patologic processes, evolutive rearrangements and lesions induced by clastogenic agents are coincident. The object of this project is to determine if those processes affect the same chromosomal sites. Primates will be used to study evolutive chromosomal rearrangements. Our research group has a wide experience in this taxonomic group. Many of the chromosomal evolution mechanisms are known, a large number of species has been studied and homeologies with human karyotype have been establised. Blood sample from primates species with known karyotypes and which homeologies with the huma
|Effective start/end date||1/01/93 → 1/01/96|
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