Effective combinational treatment of chronic pain in individual patients, by an innovative quantitative systems pharmacology pain relief approach (QSPainRelief)

Chronic pain is pain that lasts a long time, even after an injury heals. It affects more than 20 % of the population causing problems in everyday life. Chronic pain is treated with a combination of several analgesic drugs administered according to each physician’s decision based on their own best experiences. This is often not effective and it could even cause harmful effects. The EU-funded QSPainRelief project will develop a platform to improve treatment and relieve chronic pain with an effective combination of drugs thanks to a mechanism of quantitative systems pharmacology based on mathematical modelling (in silico modelling). It will allow physicians to identify and test effective, personally targeted therapy through the smart combination of drugs for each patient case.