Biologia Evolutiva d'un Sistema Modèlic en Drosophila

Project Details

Description

This project is a continuation of our previous studies on detection of mechanisms that promote biodiversity of evolutionary value in populations. We advanced significantly the understanding of these mechanisms, but these studies led us to limitations dues, mainly, to the low power of the conventional genetic markers employed. In the present project we propose to use molecular genetic markers to overcome these limitations. We will continue using the \i buzzatii\i0 complex of Drosophila as a model system. The phylogenetic relationships among the species of that complex represent a very rich set of different degrees of divergence, allowing for very precise evolutionary studies. However, there are still several uncertainties in these relationships. Using a powerful molecular approach, we propose to study in depth not only the molecular phylogeny of the complex, but also some mechanisms that, as the inversions polymorphism and the transposition of mobile elements, contribute significantly to genetic variability. This project attempts to detect those genetic factors that control fitness and morphological characters of importance for the evolution and adaptation in populations, such us body size and mating propensity. To localise these factors, we want to saturate the \i Drosophila buzzatii\i0 cytogenetic map with molecular markers whose abundance and variability will allow us to study their cosegregation with those characters of evolutionary importance. In this way, we expect to allocate the majority of variability of evolutionarty value to a finite set of genetic factors, allowing us to know the genetic basis of the previously found phenotypic correlations.
StatusFinished
Effective start/end date15/12/9715/12/00

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