BioFunctional IntraNeural Electrodes

Project Details

Description

BioFunctional IntraNeural Electrodes : In BioFINE we will develop flexible intraneural multielectrode arrays, capable of interfacing
peripheral nerves e.g. to transfer input/output signals from bionic limbs. Specifically, we address the challenge of long term tissue integration and chronic stability, by addressing three aspects of biocompatibility: 1) We develop novel fabrication methods allowing the intraneural interface to be defined at even finer resolution than before; 2) we explore functionalizations which will control the
tissue response by combined surface anchored and surface eluted agents; 3) we address structural biocompatibility on a system level by engineering novel implantable interconnects which reduced tethering forces and improve prospects for high channel count interfaces.
Fine-tuned bioactivity will safe-guard surrounding neural tissue in the initial stages of healing, and implants of sub-cellular dimensions and tissue compatible biomechanics, will safe-guard tissue healthy in the longer term. The combined approach will offer optimal conditions to bridge the gap from electrode to neuron and generate a long term functional peripheral nerve interface. Indeed, each of the three technological advancements would on their own have substantial impact on neurotechnology, reaching far beyond intraneural interfaces.
AcronymBioFINE
StatusNot started
Effective start/end date1/04/2331/03/26

Collaborative partners

  • Universitat Autònoma de Barcelona (UAB)
  • Chalmers University of Technology (lead)
  • Albert-Ludwigs-Universität Freiburg
  • Università degli Studi di Ferrara

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