Aproximación multidisciplinar a la complejidad farmacológica de las dianas de fármacos para trastornos neurológicos y psiquiátricos

Giraldo Arjonilla, Jesus (Principal Investigator)
Ortiz de Pablo, Jordi (Principal Investigator 2)
Gil Giro, Carles (Investigator)
Sabrià Pau, Josefa (Investigator)

Status	Finished
Effective start/end date	1/01/18 → 30/06/21

Funding

Spanish Ministry of Economy and Competitiveness (MINECO): €121,000.00

8 Article
1 Review article

CHIR99021 causes inactivation of Tyrosine Hydroxylase and depletion of dopamine in rat brain striatum
Hamdon, S., Fernandez-Gonzalez, P., Omar, M. Y., González-Sepúlveda, M., Ortiz, J. & Gil, C., 1 Jan 2024, In: Neuropharmacology. 242, 11 p., 109759.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
2 Downloads (Pure)
Spontaneous changes in brain striatal dopamine synthesis and storage dynamics ex vivo reveal end-product feedback-inhibition of tyrosine hydroxylase
Ortiz, J., Giraldo Arjonilla, J., Gil Giro, C., Sabrià Pau, J., Carrascal Pérez, M., Abian Moñux, J. & Vila Bover, M., 1 Jul 2022, In: Neuropharmacology. 212, 109058.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
5 Citations (Scopus)
Dynamical correlations reveal allosteric sites in g protein-coupled receptors
Renault, P. & Giraldo, J., Jan 2021, In: International journal of molecular sciences. 22, 1, p. 1-21 21 p., 187.
Research output: Contribution to journal › Article › Research › peer-review

Open Access
6 Citations (Scopus)