Projects per year
Personal profile
Education/Academic qualification
Ph. D., Ciencias (Sección Biológicas), Universitat Autònoma de Barcelona (UAB)
Award Date: 30 Jun 1977
Degree, Ciencias (Sección Biológicas), Universitat de Barcelona (UB)
Award Date: 30 Jun 1971
External positions
Profesor Titular, Universitat Autònoma de Barcelona (UAB)
1 Jan 1985 → 31 Dec 1994
Profesor Adjunto Contratado, Universitat Autònoma de Barcelona (UAB)
1 Jan 1981 → 31 Dec 1985
Asociado en Investigación, Harvard University
1 Jan 1978 → 31 Dec 1980
Profesor Adjunto Contratado, Universitat Autònoma de Barcelona (UAB)
1 Jan 1975 → 31 Dec 1978
Becario FPI, Universitat Autònoma de Barcelona (UAB)
1 Jan 1972 → 31 Dec 1975
Investigador, Institute of Biotechnology and Biomedicine "Vicent Villar Palasi" (IBB)
1 Jan 1971 → 31 Dec 1986
Profesor Ayudante, Universitat Autònoma de Barcelona (UAB)
1 Jan 1971 → 31 Dec 1972
Colaborador en investigación, Institut Provincial de Bioquímica, Clínica de Barcelona
1 Jan 1970 → 31 Dec 1971
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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STRUCTURE-BASED INHIBITORS OF ALDEHYDE DEHYDROGENASE ISOFORMS AS BIOTECHNOLOGICAL TARGETS
Farres Vicen, J. (Principal Investigator), Aviles Puigvert, F. X. (Collaborator), Covaleda Cortés, D. (Collaborator), Pares Casasampera, X. (Collaborator) & Pequerul Pavon, R. (Collaborator)
1/09/24 → 31/12/27
Project: Research Projects and Other Grants
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INVESTIGACION Y DESARROLLO DE INHIBIDORES SELECTIVOS BASADOS EN LA ESTRUCTURA DE ENZIMAS METABOLIZADORES DE ALDEHIDOS COMO DIANAS DE INTERES BIOTECNOLOGICO
Farres Vicen, J. (Principal Investigator), Aviles Puigvert, F. X. (Co-Investigador/a Principal), Alfonso Triguero, P. (Collaborator), Jimenez Aguilar, R. (Collaborator), Pequerul Pavon, R. (Collaborator), Pares Casasampera, X. (Investigator) & Vendrell Roca, J. (Investigator)
1/09/21 → 31/08/25
Project: Research Projects and Other Grants
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Proteómica de proteasas y de oxidoreductasas. Una estrategia binaria en el descubrimiento de inhibidores y su aplicabilidad biotecnológica.
Aviles Puigvert, F. X. (Principal Investigator), Farres Vicen, J. (Co-Investigador/a Principal), Lorenzo Rivera, J. (Collaborator), Pares Casasampera, X. (Investigator) & Vendrell Roca, J. (Investigator)
30/12/16 → 29/12/19
Project: Research Projects and Other Grants
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Oxidorreductasas humanas que actúan en señalización celular y desintoxicación. Estructura-función y búsqueda de inhibidores selectivos
Pares Casasampera, X. (Principal Investigator), Mesa Solis, J. (Scholar), Farres Vicen, J. (Investigator), Porté Orduna, S. E. (Investigator) & Yakovtseva , E. (Investigator)
Ministerio de Ciencia e Innovación (MICINN)
1/01/12 → 31/12/15
Project: Research Projects and Other Grants
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Estructura, bioquímica y función de oxidorreductosas humanas relacionadas con señalización celular, proliferación y apoptosis. OXIDOREDUCTASES
Pares Casasampera, X. (Principal Investigator), Porté Orduna, S. E. (Others), Yakovtseva , E. (Scholar), Farres Vicen, J. (Investigator) & Ruiz Figueras, F. X. (Investigator)
Ministerio de Educación y Ciencia (MEC)
1/01/09 → 31/12/11
Project: Research Projects and Other Grants
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Fluorescent substrates enable specific detection and structure-function insights into human aldehyde dehydrogenase isoforms
Pequerul, R., Covaleda, D., Sánchez-Vaca, A. S., Torres, L., Constantinescu, A., Perez-Alea, M., Parés, X. & Farrés, J., 5 Sept 2025, In: Chemico-Biological Interactions. 418, p. 111609 9 p., 111609.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors.
Pequerul, R., Constantinescu, A., Janji, B., Kumar, A., Baier, C., Manosalva, I., Parés, X., Palacios, O., Spicuglia, S., Colignon, D., Berrou, A., Fournet, G., Berchard, P., Martin, G., Ceylan, I., Rebollido-Rios, R., Farrés, J. & Perez-Alea, M., 16 Oct 2025, In: Cell Chemical Biology. 32, 10, p. 1260-1278.e12 1260-1278.e12.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Production, Purification, and Fluorometric Activity Assay of Human Aldehyde Dehydrogenases
Pequerul Pavon, R., Porté Orduna, S. E., Pares Casasampera, X., Pérez-Alea, M. & Farres, J., 5 Sept 2022, In: Bio-protocol. 12, 17, 14 p., e4505.Research output: Contribution to journal › Article › Research › peer-review
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Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3
Castellví, A., Pequerul, R., Barracco, V., Juanhuix, J., Parés, X. & Farres Vicen, J., 13 Apr 2022, In: Communications Biology. 5, 1, p. 354 354.Research output: Contribution to journal › Article › Research › peer-review
Open Access14 Citations (Scopus) -
Design, Synthesis, Biological Evaluation and In Silico Study of Benzyloxybenzaldehyde Derivatives as Selective ALDH1A3 Inhibitors
Ibrahim, A. I. M., Ikhmais, B., Batlle, E., Abuharb, W. K., Jha, V., Jaradat, K. T., Jiménez, R., Pequerul, R., Parés i Casasampera, X., Farrés, J. & Pors, K., 23 Sept 2021, In: Molecules. 26, 19Research output: Contribution to journal › Article › Research › peer-review
Open Access15 Citations (Scopus)
Thesis
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Estudio sobre el centro fijador de purinas de la ribonucleasa A por marcado con nucleótidos halogenados
Parés Casasampera, X. (Author), Cuchillo Foix, C. (Director), 30 Jun 1977Student thesis: Doctoral thesis
Datasets
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4XZI : Crystal structure of human Aldose Reductase complexed with NADP+ and JF0049
Ruiz, F. X. (Creator), Cousido-Siah, A. (Contributor), Domínguez, M. (Contributor), Mitschler, A. (Contributor), De Lera, Á. R. (Contributor), Parés, X. (Contributor), Farrés, J. (Contributor) & Podjarny, A. (Contributor), RCSB-PDB, 18 Nov 2015
DOI: 10.2210/pdb4xzi/pdb, https://www.rcsb.org/structure/4XZI
Dataset
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4XZH : Crystal structure of human Aldose Reductase complexed with NADP+ and JF0048
Ruiz, F. X. (Creator), Cousido-Siah, A. (Contributor), Domínguez, M. (Contributor), Mitschler, A. (Contributor), De Lera, Á. R. (Contributor), Parés, X. (Contributor), Farrés, J. (Contributor) & Podjarny, A. (Contributor), RCSB-PDB, 18 Nov 2015
DOI: 10.2210/pdb4xzh/pdb, https://www.rcsb.org/structure/4XZH
Dataset
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4WEV : Crystal structure of human AKR1B10 complexed with NADP+ and sulindac
Cousido-Siah, A. (Creator), Ruiz, F. X. (Contributor), Crespo, I. (Contributor), Porté, S. (Contributor), Mitschler, A. (Contributor), Parés, X. (Contributor), Podjarny, A. (Contributor) & Farrés, J. (Contributor), RCSB-PDB, 11 Sept 2014
DOI: 10.2210/pdb4wev/pdb, https://www.rcsb.org/structure/4WEV
Dataset
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4XZL : Crystal structure of human AKR1B10 complexed with NADP+ and JF0049
Ruiz, F. X. (Creator), Cousido-Siah, A. (Contributor), Domínguez, M. (Contributor), Mitschler, A. (Contributor), De Lera, Á. R. (Contributor), Parés, X. (Contributor), Farrés, J. (Contributor) & Podjarny, A. (Contributor), RCSB-PDB, 18 Nov 2015
DOI: 10.2210/pdb4xzl/pdb, https://www.rcsb.org/structure/4XZL
Dataset