Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Ph. D., Ciències (Biològiques), Universitat Autònoma de Barcelona (UAB)
Award Date: 11 Jan 1995
Masters, Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona (UAB)
Award Date: 28 Jul 1993
Degree, Biologia, Universitat Autònoma de Barcelona (UAB)
Award Date: 13 Sept 1989
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Collaborations and top research areas from the last five years
Projects
- 15 Finished
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Fragmentos de anticuerpos de cadena sencilla bifuncionales como una nueva aproximación terapéutica a la enfermedad de Alzheimer
Villegas Hernandez, S. (Principal Investigator) & Martí-Clua, J. (Investigator)
Spanish Ministry of Economy and Competitiveness (MINECO)
1/01/18 → 31/08/21
Project: Research Projects and Other Grants
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Efficiency and safety in vivo studies of a promising re-engineered antibody fragment derived from bapineuzumab to cure Alzheimer's disease
Villegas Hernandez, S. (Principal Investigator), Lope Piedrafita, S. (Others), Esquerda Canals, G. (Scholar), Güell Bosch, J. (Scholar), Montoliu Gaya, L. (Scholar) & Martí-Clua, J. (Investigator)
Agency for Management of University and Research Grants (AGAUR), European Regional Development Fund (FEDER)
30/07/15 → 29/07/17
Project: Research Projects and Other Grants
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Eficacia y seguridad de un fragmento de bapineuzumab como terapia de la enfermedad de Alzheimer en un modelo murino. Implicación de las apolipoproteínas en el aclaramiento.
Villegas Hernandez, S. (Principal Investigator), Esqueda, G. (Scholar), Güell Bosch, J. (Scholar), Montoliu Gaya, L. (Scholar) & Martí-Clua, J. (Investigator)
Instituto de Salud Carlos III (ISCIII)
1/01/14 → 31/12/17
Project: Research Projects and Other Grants
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Inmunoterapia con fragmentos de anticuerpos en la enfermedad de alzheimer: bases moleculares y ensayos en el ratón triple trangénico 3xTg-AD
Villegas Hernandez, S. (Principal Investigator), Geovanny Rivera Hernández (Investigator), Marin Argany, M. (Investigator) & Martí-Clua, J. (Investigator)
Instituto de Salud Carlos III (ISCIII)
1/01/11 → 31/12/13
Project: Research Projects and Other Grants
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Diseño racional de anticuerpos humanizados como terapía de la enfermedad de Alzheimer: Ensayos en un modulo triple tragénico (3xTg-AD)
Villegas Hernandez, S. (Principal Investigator), Geovanny Rivera Hernández (Scholar), Marin Argany, M. (Scholar), Gimenez Llort, L. (Investigator), Manzo Rodríguez, L. (Investigator) & Verdú Navarro, E. (Investigator)
Fundación Investigación Médica Mútua Madrileña
29/09/08 → 29/09/11
Project: Research Projects and Other Grants
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Amyloid-beta peptide and tau protein crosstalk in Alzheimer's disease
Villegas Hernández, S., Ramos Roda, A., Montoliu-Gaya, L. & Tiessler, L., 2022, In: Neural Regeneration Research. 17, 8, p. 1666-1674 9 p.Research output: Contribution to journal › Review article › Research › peer-review
Open Access138 Citations (Scopus) -
Both Amyloid-β Peptide and Tau Protein Are Affected by an Anti-Amyloid-β Antibody Fragment in Elderly 3xTg-AD Mice
Ramos Roda, A., Montoliu Gaya, L., Serra-Mir, G. & Villegas Hernández, S., 2020, In: International Journal of Molecular Sciences. 21, 18Research output: Contribution to journal › Article › Research › peer-review
Open Access14 Citations (Scopus) -
Cognitive Impairment in the 3xTg-AD Mouse Model of Alzheimer's Disease is Affected by A beta-ImmunoTherapy and Cognitive Stimulation
Roda, A. R., Villegas, S., Esquerda-Canals, G. & Martí-Clúa, J., 2 Oct 2020, In: Pharmaceutics. 12, 10, p. 1-21 21 p., 944.Research output: Contribution to journal › Article › Research › peer-review
Open Access27 Citations (Scopus) -
Molecular basis for the protective effects of low-density lipoprotein receptor-related protein 1 (LRP1)-derived peptides against LDL aggregation
Benitez-Amaro, A., Pallara, C., Nasarre, L., Rivas-Urbina, A., Benitez, S., Vea, A., Bornachea, O., de Gonzalo-Calvo, D., Serra-Mir, G., Villegas, S., Prades, R., Sanchez-Quesada, J. L., Chiva, C., Sabido, E., Tarragó, T. & Llorente-Cortés, V., 1 Jul 2019, In: Biochimica et Biophysica Acta - Biomembranes. 1861, 7, p. 1302-1316 15 p.Research output: Contribution to journal › Article › Research
15 Citations (Scopus) -
Pharmacokinetic parameters and mechanism of action of an efficient anti-Aβ single chain antibody fragment
Esquerda-Canals, G., Martí-Clúa, J. & Villegas, S., 31 May 2019, In: PLoS ONE. 14, 5, p. e0217793 20 p., 0217793.Research output: Contribution to journal › Article › Research › peer-review
11 Citations (Scopus)
Thesis
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Caracterización detallada del proceso de activación de la procarboxipeptidasa B mediante el uso de inhibidores. Diseño y construcción de mutantes del segmento de activación
Villegas Hernández, S. (Author), Avilés Puigvert, F. X. (Director), 22 Dec 1994Student thesis: Doctoral thesis
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Detección y caracterización de intermediarios en el proceso de activación de la procarboxipeptidasa B porcina
Villegas Hernandez, S. (Author), Avilés Puigvert, F. X. (Director), 9 Sept 1991Student thesis: Dissertation (TFM)
Datasets
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MOESM2 of Functional inclusion bodies produced in the yeast Pichia pastoris
Rueda, F. (Creator), Gasser, B. (Creator), Sánchez Chardi, A. D. (Creator), Roldán Molina, M. (Contributor), Villegas Hernandez, S. (Creator), Puxbaum, V. (Creator), Ferrer-Miralles, N. (Creator), Unzueta, U. (Creator), Vázquez, E. (Creator), Garcia-Fruitós, E. (Creator), Mattanovich, D. (Creator) & Villaverde, A. (Creator), figshare, 1 Oct 2016
DOI: 10.6084/m9.figshare.c.3596801_d3.v1, https://springernature.figshare.com/articles/dataset/MOESM2_of_Functional_inclusion_bodies_produced_in_the_yeast_Pichia_pastoris/4320014/1
Dataset