Projects per year
Personal profile
Education/Academic qualification
Ph. D., Doctorat en Ciències Químiques, Universitat Autònoma de Barcelona (UAB)
Award Date: 1 Jan 1985
Degree, Llicenciat en Ciències Químiques, amb Grau, Universitat Autònoma de Barcelona (UAB)
Award Date: 1 Jan 1980
External positions
Investigador programa propi, Universitat Autònoma de Barcelona (UAB)
1 Jan 1991 → 31 Dec 1993
Instructor / Research Associate, Baylor College of Medicine (BCM)
1 Jan 1989 → 31 Dec 1991
Postdoctoral Research Associate, Purdue University
1 Jan 1986 → 31 Dec 1988
Colaborador Investigació, Universitat Autònoma de Barcelona (UAB)
1 Jan 1986 → 31 Dec 1986
Becari F.P.I., Universitat Autònoma de Barcelona (UAB)
1 Jan 1982 → 31 Dec 1985
Becari I.N.A.P.E., Universitat Autònoma de Barcelona (UAB)
1 Jan 1981 → 31 Dec 1981
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Dive into the research topics where Jaime Farres Vicen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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STRUCTURE-BASED INHIBITORS OF ALDEHYDE DEHYDROGENASE ISOFORMS AS BIOTECHNOLOGICAL TARGETS
Farres Vicen, J. (Principal Investigator), Aviles Puigvert, F. X. (Collaborator), Covaleda Cortés, D. (Collaborator), Pares Casasampera, X. (Collaborator) & Pequerul Pavon, R. (Collaborator)
1/09/24 → 31/12/27
Project: Research Projects and Other Grants
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INVESTIGACION Y DESARROLLO DE INHIBIDORES SELECTIVOS BASADOS EN LA ESTRUCTURA DE ENZIMAS METABOLIZADORES DE ALDEHIDOS COMO DIANAS DE INTERES BIOTECNOLOGICO
Farres Vicen, J. (Principal Investigator), Aviles Puigvert, F. X. (Co-Investigador/a Principal), Alfonso Triguero, P. (Collaborator), Jimenez Aguilar, R. (Collaborator), Pequerul Pavon, R. (Collaborator), Pares Casasampera, X. (Investigator) & Vendrell Roca, J. (Investigator)
1/09/21 → 31/08/25
Project: Research Projects and Other Grants
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Proteómica de proteasas y de oxidoreductasas. Una estrategia binaria en el descubrimiento de inhibidores y su aplicabilidad biotecnológica.
Aviles Puigvert, F. X. (Principal Investigator), Farres Vicen, J. (Co-Investigador/a Principal), Lorenzo Rivera, J. (Collaborator), Pares Casasampera, X. (Investigator) & Vendrell Roca, J. (Investigator)
30/12/16 → 29/12/19
Project: Research Projects and Other Grants
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Oxidorreductasas humanas que actúan en señalización celular y desintoxicación. Estructura-función y búsqueda de inhibidores selectivos
Pares Casasampera, X. (Principal Investigator), Mesa Solis, J. (Scholar), Farres Vicen, J. (Investigator), Porté Orduna, S. E. (Investigator) & Yakovtseva , E. (Investigator)
Ministerio de Ciencia e Innovación (MICINN)
1/01/12 → 31/12/15
Project: Research Projects and Other Grants
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Estructura, bioquímica y función de oxidorreductosas humanas relacionadas con señalización celular, proliferación y apoptosis. OXIDOREDUCTASES
Pares Casasampera, X. (Principal Investigator), Porté Orduna, S. E. (Others), Yakovtseva , E. (Scholar), Farres Vicen, J. (Investigator) & Ruiz Figueras, F. X. (Investigator)
Ministerio de Educación y Ciencia (MEC)
1/01/09 → 31/12/11
Project: Research Projects and Other Grants
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Discovery of a reversible ALDH1A3 inhibitor through a consensus docking-based virtual screening study
Batlle, E., Pequerul, R., Farrés, J., Eriksson, L. A., Pors, K. & Jha, V., 31 Aug 2025, In: Journal of Computer-Aided Molecular Design. 39, 22 p., 72.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Fluorescent substrates enable specific detection and structure-function insights into human aldehyde dehydrogenase isoforms
Pequerul, R., Covaleda, D., Sánchez-Vaca, A. S., Torres, L., Constantinescu, A., Perez-Alea, M., Parés, X. & Farrés, J., 5 Sept 2025, In: Chemico-Biological Interactions. 418, p. 111609 9 p., 111609.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Web of Science) -
Inter- and intra-tumoral ALDH1 heterogeneity in breast cancer identifies therapeutic opportunities for ALDH1A-specific inhibitors.
Pequerul, R., Constantinescu, A., Janji, B., Kumar, A., Baier, C., Manosalva, I., Parés, X., Palacios, O., Spicuglia, S., Colignon, D., Berrou, A., Fournet, G., Berchard, P., Martin, G., Ceylan, I., Rebollido-Rios, R., Farrés, J. & Perez-Alea, M., 16 Oct 2025, In: Cell Chemical Biology. 32, 10, p. 1260-1278.e12 1260-1278.e12.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Downloads (Pure) -
Upregulation of ALDH1 as an adaptive epigenetic response to anthracyclines in acute myeloid leukemia.
Leonetti, F., Kosanovic, S., Rebollidos-Rios, R., Manosalva, I., Baier, C., Yazir, M., Constantinescu, A., Souaid, C., Pequerul, R., MK, A., Shaikh, M., Havlová, M., Costello, R., Farrés, J., Martin, G., Alberich-Jorda, M., Spicuglia, S. & Perez-Alea, M., 28 Oct 2025, In: HemaSphere. 9, 10, 20 p., e70244.Research output: Contribution to journal › Article › Research › peer-review
Open Access1 Citation (Scopus) -
ALDH1 subtype-specific inhibitor targets key cell populations in triple negative breast cancer
Pequerul, R., Constantinescu, A., Janji, B., Kumar, A., Parés, X., Palacios, O., Colignon, D., Berrou, A., Fournet, G., Martin, G., Ceylan, I., Rebollido-Ríos, R., Farrés, J. & Perez-Alea, M., 4 Jan 2024, In: bioRxiv. 42 p.Research output: Contribution to journal › Article › Research
Open Access
Thesis
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Alcohol deshidrogenasa i aldehid deshidrogenasa de placenta humana
Farrés Vicén, J. (Author), Parés Casasampera, X. (Director), 17 Dec 1985Student thesis: Doctoral thesis
Datasets
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4XZI : Crystal structure of human Aldose Reductase complexed with NADP+ and JF0049
Ruiz, F. X. (Creator), Cousido-Siah, A. (Contributor), Domínguez, M. (Contributor), Mitschler, A. (Contributor), De Lera, Á. R. (Contributor), Parés, X. (Contributor), Farrés, J. (Contributor) & Podjarny, A. (Contributor), RCSB-PDB, 18 Nov 2015
DOI: 10.2210/pdb4xzi/pdb, https://www.rcsb.org/structure/4XZI
Dataset
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4XZH : Crystal structure of human Aldose Reductase complexed with NADP+ and JF0048
Ruiz, F. X. (Creator), Cousido-Siah, A. (Contributor), Domínguez, M. (Contributor), Mitschler, A. (Contributor), De Lera, Á. R. (Contributor), Parés, X. (Contributor), Farrés, J. (Contributor) & Podjarny, A. (Contributor), RCSB-PDB, 18 Nov 2015
DOI: 10.2210/pdb4xzh/pdb, https://www.rcsb.org/structure/4XZH
Dataset
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4XZL : Crystal structure of human AKR1B10 complexed with NADP+ and JF0049
Ruiz, F. X. (Creator), Cousido-Siah, A. (Contributor), Domínguez, M. (Contributor), Mitschler, A. (Contributor), De Lera, Á. R. (Contributor), Parés, X. (Contributor), Farrés, J. (Contributor) & Podjarny, A. (Contributor), RCSB-PDB, 18 Nov 2015
DOI: 10.2210/pdb4xzl/pdb, https://www.rcsb.org/structure/4XZL
Dataset
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5M2F : Crystal structure of human AKR1B10 complexed with NADP+ and the synthetic retinoid UVI2008
Ruiz, F. X. (Creator), Álvarez, S. (Contributor), Porté, S. (Contributor), Cousido-Siah, A. (Contributor), Mitschler, A. (Contributor), de Lera, Á. R. (Contributor), Parés, X. (Contributor), Podjarny, A. (Contributor) & Farrés, J. (Contributor), 15 Feb 2017
DOI: 10.2210/pdb5m2f/pdb, https://www.rcsb.org/structure/5M2F
Dataset