Laboratori d'Enginyeria Genètica Animal i Teràpia Gènica

  • Postal addressShow on map

    Edifici H. Campus de la UAB

    08193 Bellaterra (Cerdanyola del Vallès)

    Spain

Organisation profile

Organisation profile

Our research focuses on developing gene therapy approaches for highly prevalent diseases, such as diabetes mellitus and obesity, and rare metabolic/neurodegenerative diseases. Obesity and type 2 diabetes, strongly associated with deficits in cognitive function, are a major health problem because of their alarming growing prevalence worldwide. Novel adeno-associated viral (AAV) vector-mediated gene therapy strategies are used to target these pathophysiological processes. We are also developing gene therapies for Mucopolysaccharidosis, a group of devastating lysosomal storage diseases that currently lack effective treatments. We aim at developing gene therapies that are minimally invasive, safe and could guarantee maximal efficacy in the most affected organs. The know-how derived from these studies is also used to assess the effectiveness of AAV-based gene therapeutics products to counteract other neurodegenerative diseases and rare diseases affecting the skeletal system in mouse models.

Directed by:

Fàtima Bosch Tubert

Research lines

  • Research lines:
  • GENE THERAPY APPROACHES FOR DIABETES MELLITUS, OBESITY AND ASSOCIATED COMORBIDITIES
  • GENE THERAPY APPROACHES FOR RARE METABOLIC AND NEUROGENERATIVE DISEASES
  • GENE THERAPY FOR HIGHLY PREVALENT NEURODEGENERATIVE DISEASES

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Fingerprint

Dive into the research topics where Laboratori d'Enginyeria Genètica Animal i Teràpia Gènica is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or