Projects per year
Organisation profile
Organisation profile
In 2003, researchers with different backgrounds (biology, psychology, medicine, etc.) investigating the nervous system at the Universitat Autònoma de Barcelona (UAB), created a platform to join forces and build synergies between groups. Since then, the Institute has been growing, and nowadays there are around 200 members, among researchers, students and support staff.
The main strategic goal is to leave traditional disciplines behind, and from a multidisciplinary and translational approach, investigate the challenges posed by neurosciences in the XXI century: neurodegeneration, neuroregeneration, how the healthy brain works, what happens when it gets sick, and how we could cure it.
We explore all levels of biological organization: from molecular interactions to complex behaviors, using cell cultures, animal models or human patients. The final objective is to find new molecular, cellular, genetic and psychological therapies to nervous system pathologies.
Directed by:
Carlos Alberto Saura Antolin
Research lines
- Research lines:
- Cognitive disorders in aging and neurodegeneration.
- Motor disorders of the nervous system.
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Collaborations and top research areas from the last five years
Profiles
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TRANSCANN: Decoding Cell Type-Specific Translatomics in Memory and Structural Plasticity Changes Induced by Cannabis
Puighermanal Puigvert, E. (Principal Investigator)
1/04/25 → 31/03/27
Project: Research Projects and Other Grants
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NERO-ALS: Neuroresolving Therapeutics: Developing Innovative Treatments to Combat Neuroinflammation in Degenerative Diseases with a Focus on ALS
Lopez Vales, R. (Principal Investigator), Arbulu Fernandez, M. (Collaborator), Caro Cantón, M. (Predoctoral), Garcia Garcia, J. (Predoctoral) & Goytisolo Gil Moreno de Mora, F. A. (Technician)
14/01/25 → 13/01/26
Project: Research Projects and Other Grants
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Defining a Minimal Human Endogenous Promoter for Safe and Efficient Gene Therapy to Treat MLC
Bosch, A. (Principal Investigator), Chillón Rodriguez, M. (Investigator), Sanchez Osuna, A. (Investigator), Brao Gonzalez, A. (Predoctoral), Rodriguez Reverte, I. (Predoctoral) & Miravet Delgado, S. (Technician)
1/01/25 → 31/12/25
Project: International research project
Research output
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Gene therapy rescues brain edema and motor function in a mouse model of megalencephalic leukoencephalopathy with subcortical cysts
Brao, A., Sanchez, A., Rodríguez, I., Rey, J. D., Lope-Piedrafita, S., Prat, E., Nunes, V., Chillon, M., Estévez, R. & Bosch, A., 2 Apr 2025, In: Molecular Therapy. 33, 4, p. 1434-1448 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
HEBE: A novel chimeric chronokine for ameliorating memory deficits in Alzheimer's disease
Esandi, J., Renault, P., Capilla-López, M. D., Blanch, R., Edo, Á., Ramirez-Gómez, D., Bosch, A., Almolda, B., Saura, C. A., Giraldo, J. & Chillón, M., Feb 2025, In: Biomedicine and Pharmacotherapy. 183, 13 p., 117815.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Les distopies no avisen: distopies, el paper de la ciència
Chanes Puiggros, L. & Vilarroya, O., 2025, In: Serra d'Or. 781, p. 22-23 1 p.Research output: Contribution to journal › Article › Research › peer-review
Datasets
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Label noise in subtype discrimination of class C G protein-coupled receptors: A systematic approach to the analysis of classification errors
König, C. (Creator), Cárdenas, M. I. (Creator), Giraldo, J. (Creator), Alquézar, R. (Creator) & Vellido, A. (Creator), figshare, 29 Sept 2015
DOI: 10.6084/m9.figshare.c.3623084, https://figshare.com/collections/Label_noise_in_subtype_discrimination_of_class_C_G_protein-coupled_receptors_A_systematic_approach_to_the_analysis_of_classification_errors/3623084
Dataset
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GNAO1 encephalopathy: further delineation of a severe neurodevelopmental syndrome affecting females
Marc�-Grau, A. (Contributor), Dalton, J. (Creator), L�pez-Pis�n, J. (Contributor), Monge-Galindo, L. (Creator), Cuenca-Le�n, E. (Contributor), Giraldo, J. (Creator) & Macaya, A. (Creator), figshare, 12 Apr 2016
DOI: 10.6084/m9.figshare.c.3646136, https://figshare.com/collections/GNAO1_encephalopathy_further_delineation_of_a_severe_neurodevelopmental_syndrome_affecting_females/3646136
Dataset
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Additional file 1 of Label noise in subtype discrimination of class C G protein-coupled receptors: A systematic approach to the analysis of classification errors
König, C. (Creator), Cárdenas, M. I. (Creator), Giraldo, J. (Creator), Alquézar, R. (Creator) & Vellido, A. (Creator), figshare, 29 Sept 2015
DOI: 10.6084/m9.figshare.c.3623084_d1.v1, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Label_noise_in_subtype_discrimination_of_class_C_G_protein-coupled_receptors_A_systematic_approach_to_the_analysis_of_classification_errors/4400093/1
Dataset
Student theses
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Alteració dels nivells de 5-hidroxitriptamina en el SNC de rata per acció directa de la toxina tetànica en les terminacions nervioses triptaminèrgiques
López Barcons, L. A. (Author), Aguilera Ávila, J. (Director), 15 Jul 1990Student thesis: Dissertation (TFM)
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Análisis de las alteraciones magnetoencefalográficas en pacientes con trastornos del espectro autista
Montserrat Palau Baduell (Author), Tomás Ortiz Alonso (Director) & Fernández Teruel, A. (Director), 5 Jul 2017Student thesis: Doctoral thesis
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Gene therapy targeting neuregulins for the treatment of amiotrophic lateral sclerosis.
Modol Caballero, G. (Author), Navarro Acebes, X. (Tutor), Herrando Grabulosa, M. (Director) & Navarro Acebes, X. (Director), 12 Jul 2019Student thesis: Doctoral thesis