Projects per year
Organisation profile
Organisation profile
El nostre Grup utilitza un enfoc multidisciplinari per l’estudi de l’estructura, la funció i
l’agregació de proteïnes. Pretenem conèixer com aquests fenòmens es relacionen amb un conjunt
de patologies humanes que inclouen malalties neurodegeneratives com el Parkinson, patologies
rares com l’amiloïdosi familiar, així com malalties causades per agents infecciosos com
Plasmodium i Micoplasma. El nostre objectiu és desenvolupar sistemes de diagnòstic i
aproximacions terapèutiques innovadores per cadascuna d’aquestes malalties, atacant de manera
específica les conformacions proteiques que les causen. Les tècniques emprades inclouen
bioinformàtica, biofísica, cristal·lografia de raigs-X, disseny de lligands, crio-microscopia
electrònica, proteòmica, biologia molecular i cel·lular i tècniques per a l'estudi de molècules
individuals.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Dive into the research topics where Grup d’estructura i agregació de proteïnes is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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PROTEIN AGGREGATION: IMPLEMENTING NEW BIOMEDICAL, STRUCTURAL AND NANOTECHNOLOGICAL STRATEGIES
Ventura Zamora, S., Pallares Goitiz, I., Bartolome Nafria, A., Behbahanipour ., M., Fornt i Suñé, M., Garcia Pardo, J., Manglano Artuñedo, Z., Navarro Cantero, S., Peña Diaz, S., Pintado Grima, C., Serra Hartmann, X., Burdukiewicz, M., Pinheiro, F. & Santos, J.
1/09/23 → 31/08/26
Project: Research Projects and Other Grants
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In vivo assessment of the potential of human helical peptides to treat Parkinson's Disease
21/12/22 → 20/12/23
Project: Research Projects and Other Grants
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STRUCTURAL AND FUNCTIONAL INSIGHTS INTO THE UBIQUITIN/SUMO CONJUGATION AND DECONJUGATION PATHWAY
1/09/22 → 31/08/25
Project: Research Projects and Other Grants
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Author Correction: Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity (Nature Communications, (2016), 7, 1, (10787), 10.1038/ncomms10787): Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity
Sant’Anna, R., Gallego, P., Robinson, L. Z., Pereira-Henriques, A., Ferreira, N., Pinheiro, F., Esperante, S., Pallares, I., Huertas, O., Almeida, M. R., Reixach, N., Insa, R., Velazquez-Campoy, A., Reverter, D., Reig, N. & Ventura, S., 3 Feb 2023, In: Nature communications. 14, 1, 582.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Biofabrication of Self-Assembling Covalent Protein Nanoparticles through Histidine-Templated Cysteine Coupling
López-Laguna, H., Rueda, A., Martínez-Torró, C., Sánchez-Alba, L., Carratalá, J. V., Atienza-Garriga, J., Parladé, E., Sánchez, J. M., Serna, N., Voltà-Durán, E., Ferrer-Miralles, N., Reverter, D., Mangues, R., Villaverde, A., Vázquez, E. & Unzueta, U., 13 Mar 2023, In: ACS Sustainable Chemistry and Engineering. 11, 10, p. 4133-4144 12 p.Research output: Contribution to journal › Article › Research › peer-review
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Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3
Garcia-Pardo, J., Bartolomé-Nafría, A., Chaves-Sanjuan, A., Gil-Garcia, M., Visentin, C., Bolognesi, M., Ricagno, S. & Ventura, S., 16 Jan 2023, In: Nature communications. 14, 1, 239.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus)
Datasets
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Transcriptional response to metal starvation in the emerging pathogen Mycoplasma genitalium is mediated by Fur-dependent and –independent regulatory pathways
Martinez Torro, C. (Creator), Torres Puig, S. (Creator), Monge, M. (Creator), Sanchez Alba, L. (Creator), González-Martín, M. (Creator), Marcos-Silva, M. (Creator), Peralvarez-Marin, A. (Creator), Canals, F. (Creator), Querol Murillo, E. (Creator), Piñol Ribas, J. (Creator) & Quijada Pich, O. (Creator), 20 Dec 2019
DOI: 10.6084/m9.figshare.11418321.v1, https://tandf.figshare.com/articles/dataset/Transcriptional_response_to_metal_starvation_in_the_emerging_pathogen_i_Mycoplasma_genitalium_i_is_mediated_by_Fur-dependent_and_independent_regulatory_pathways/11418321/1
Dataset
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Transcriptional response to metal starvation in the emerging pathogen Mycoplasma genitalium is mediated by Fur-dependent and –independent regulatory pathways
Martinez Torro, C. (Creator), Torres-Puig, S. (Creator), Monge, M. (Creator), Sanchez Alba, L. (Creator), González-Martín, M. (Creator), Marcos Silva, M. (Creator), Peralvarez-Marin, A. (Creator), Canals, F. (Creator), Querol Murillo, E. (Creator), Piñol Ribas, J. (Creator) & Quijada Pich, O. (Creator), 20 Jan 2023
DOI: 10.6084/m9.figshare.11418321.v3, https://tandf.figshare.com/articles/dataset/Transcriptional_response_to_metal_starvation_in_the_emerging_pathogen_i_Mycoplasma_genitalium_i_is_mediated_by_Fur-dependent_and_independent_regulatory_pathways/11418321/3
Dataset
Student theses
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Expresión, purificación y cristalización de las proteínas del complejo SMC5/6.
Author: Lascorz Lozano, J. A., 2015Supervisor: Reverter Cendros, D. (Director)
Student thesis: Dissertation (TFM)
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Structural studies on Protein-Protein interactions: Analysis of the regulation of the DYBLL/LC8 binding to NEK9 and characterization of the enzymes composing the arginine deiminase pathway Mycoplasma penetrans.
Author: Gallego Alonso, P., Nov 2014Supervisor: Reverter Cendros, D. (Director)
Student thesis: Doctoral thesis
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Structural and Funcional Studies on the Regulation of the USP28 de-ubiquitinase and the SENP5 de-SUMOylase
Author: Yang , Z., Nov 2014Supervisor: Reverter Cendros, D. (Director)
Student thesis: Doctoral thesis