Projects per year
Organisation profile
Organisation profile
The research group is focused on defining and applying gene therapy strategies for the
treatment of diseases that affect the Nervous System such as neurodegenerative and
neurometabolic diseases, as well as in the study of the molecular mechanisms involved in the
development and progression of pathological processes. This main objective is defined in 3 main
lines: 1.- Development of gene therapy strategies for rare diseases affecting the central
nervous system. 2.- Study of the molecular mechanisms involved in cognitive deficits in aging
and Alzheimer's. 3.- Development, generation, and production of gene therapy vectors.
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
Fingerprint
Dive into the research topics where Gene therapy for diseases involving the central nervous system- TherCNS is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
-
Assumpció Bosch
- Department of Biochemistry and Molecular Biology
- Gene therapy for diseases involving the central nervous system- TherCNS
- Institute of Neuroscience (INc)
Person: Professor (non-goverment employee), Assignment to research
-
Alejandro Brao Gonzalez
- Department of Biochemistry and Molecular Biology
- Gene therapy for diseases involving the central nervous system- TherCNS
Person: University Training FPU 3-4, Assignment to research
-
Miguel Chillón Rodriguez
- Department of Biochemistry and Molecular Biology - ICREA Research staff
- Gene therapy for diseases involving the central nervous system- TherCNS
- Institute of Neuroscience (INc)
Person: Visiting scholar, Assignment to research, Adjunct lecturer (non-goverment employee)
-
MLC: Gene therapy to treat Megalencephalic Leukodystrophy with subcortical cysts (MLC)
Bosch, A., Brao Gonzalez, A., Chillón Rodriguez, M., Lunar Roldan, J., Miravet Delgado, S. & Sanchez Osuna, A.
20/03/23 → 19/03/25
Project: International research project
-
KLOTHOxALS: Chronokine gene theapy, a new approach to tackle amyotrophic lateral sclerosis
Bosch, A., Rey Azpiri, J. D., Sanchez Osuna, A. & Sinkule, J.
19/10/22 → 18/04/24
Project: Research Projects and Other Grants
-
EPILEP: Plataforma personalitzada per l'anàlisi de fàrmacs antiepilèptics
Chillón Rodriguez, M., Espinosa Parrilla, J. F., Martin Pinardi, L., Rodriguez Estevez, L., Blanquez Caurel, D. & Manuel Toledo Argany
11/10/22 → 10/07/23
Project: Research Projects and Other Grants
-
Differential toxicity profile of secreted and processed α-Klotho expression over mineral metabolism and bone microstructure
Bosch i Merino, A., Chillón Rodríguez, M., Roig-Soriano, J., Sánchez-de-Diego, C., Esandi-Jauregui, J., Verdés, S., Abraham, C. R. & Ventura, F., 2023, In: Scientific Reports. 13Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Gemfibrozil, a lipid-lowering drug, improves hepatorenal damages in a mouse model of aging
Hakimizadeh, E., Tadayon, S., Zamanian, M. Y., Soltani, A., Giménez-Llort, L., Hassanipour, M. & Fatemi, I., Jun 2023, In: Fundamental and Clinical Pharmacology. 37, 3, p. 599-605 7 p.Research output: Contribution to journal › Article › Research › peer-review
1 Citation (Scopus) -
Sex-dependent worsening of NMDA-induced responses, anxiety, hypercortisolemia, and organometry of early peripheral immunoendocrine impairment in adult 3xTg-AD mice and their long-lasting ontogenic modulation by neonatal handling
Baeta-Corral, R., De la Fuente, M. & Giménez-Llort, L., 13 Feb 2023, In: Behavioural Brain Research. 438, 11 p., 114189.Research output: Contribution to journal › Article › Research › peer-review
Open Access