Projects per year
Organisation profile
Organisation profile
El Departament de Genètica i de Microbiologia (DGM) és l’ encarregat d’organitzar i desenvolupar la investigació així com d’impartir la docència de les disciplines incloses en les àrees de la Genètica i la Microbiologia.
Es tracta d’un departament interfacultatiu, format per tres unitats departamentals, dues ubicades a la Facultat de Biociències (Unitat de Genètica i Unitat de Microbiologia Campus) i la tercera (Unitat de Microbiologia Medicina) integrada pel personal docent i investigador de l’àrea de Microbiologia de les Unitats docents hospitalàries de la UAB: U.D. Sant Pau; U.D. Vall d'Hebron; U.D. Hospital del Mar, U.D. Germans Trias i Pujol i G.D. Parc Taulí.
L’activitat del DGM està totalment compromesa en participar en l'aventura intel•lectual sense precedents que representa la Biologia del segle XXI. Aspirem (i) a contribuir amb la nostra capacitat i la nostra dedicació al progrés científic realitzant una investigació d’excel·lència en les àrees de la Genètica i de la Microbiologia; (ii) a proporcionar una formació de qualitat als nostres estudiants, futurs investigadors, docents i professionals en aquestes àrees; i (iii) a col·laborar a augmentar el benestar de la nostra societat mitjançant l’aplicació pràctica dels nostres coneixements en la Medicina i diferents sectors industrials com el de la biotecnologia, aliments, farmàcia i medi ambient entre d’altres.
Directed by:
Alba Hernandez Bonilla
Research lines
- Research lines:
- Causes and consequences of chromosomal rearrangements.
- Evolutionary impact of transposable elements.
- Molecular and structural evolution of genomes.
- Genetic and ecological mechanisms that promote biodiversity in natural communities.
- Molecular evolution of mobile genetic elements in interspecific hybrids and in natural colonizing populations.
- Genetic architecture of the species.
- Genetic basis of thermal adaptation.
- Evolutionary potential of endemic species.
- Evolution of primitive genetic systems.
- Study of the structure of natural Drosophila populations using molecular markers.
- Molecular phylogeny of the complex buzzati (group replete; genus Drosophila).
- Molecular evolution of mobile genetic elements in interspecific hybrids and in natural populations.
- Interspecific hybrid genetic instability due to transposition of mobile elements in Drosophila.
- Expression of the Osvaldo retrotransposon in lines and interspecific hybrids of Drosophila.
- Taxes of occupation of transposable elements in original populations and colonizers of Drosophila using the "in situ" hybridization technique in polytechnic chromosomes.
- Bioinformatic analysis of nucleotide diversity.
- Genotype-phenotype association.
- Mathematical models of pattern formation and morphological evolution.
- Morphometry of embryos and evolution.
- Biomonitoring of human populations for the determination of the genetic risk of environmental, occupational or therapeutic exposures.
- Genetic polymorphisms as individual susceptibility factors.
- Detection and mechanisms of genotoxicity of environmental contaminants.
- Genetics or molecular biology of Fanconi anemia and other rare diseases resulting from errors in the repair of DNA lesions.
- Molecular bases of the pathogenesis and drug resistance of Mycobacterium tuberculosis.
- Detection and characterization of resistance mechanisms, mainly resistance to beta lactams in enterobacteria.
- Detection and characterization of resistance to antituberculosis drugs in mycobacterium and the current epidemiology.
- Rapid diagnosis of infectious diseases with special interest in Virology, Parasitology and Mycology.
- Design of microbial sensors for biotechnological, clinical and environmental applications.
- Effect of pollutants: hydrocarbons and metals on microorganism populations in natural and artificial environments.
- Study of microbial diversity in agricultural systems. Impact of phytosanitary treatments.
- Genomics of bacterial pathogens aimed at the identification of virulence factors and the design of new vaccines.
- Use of environmental mycobacteria in the study of tuberculosis and cancer treatment.
- Mechanisms of regulation of gene expression in pathogenic bacteria.
- Synthesis of DNA precursors and pathogenesis.
- Study of the mechanisms of resistance to antibacterials.
- Biotechnological applications of bacteria.
Fingerprint
Collaborations and top research areas from the last five years
Profiles
-
Mohamed Alaraby Abdalaziz Mohamed
Person: Beatriu de Pinós researcher's programme, Affiliation to research
-
BIOGRAN: Evaluation of biomimetic granules for the sustained delivery of therapeutic proteins
Vazquez Gomez, E. (Principal Investigator), Parlade Molist, E. (Investigator), Sanchez Quiroga, J. M. (Investigator), Teixeira de Pinho Favaro, M. (Investigator), Villaverde Corrales, A. P. (Investigator), Voltà Durán, E. (Investigator), López Laguna, H. (Others), Martin Pinardi, L. (Others) & Resina Rodríguez, D. (Others)
21/12/24 → 20/08/25
Project: Research Projects and Other Grants
-
META-BEAT: Microbial enzyme targeting metabolism for cancer treatment
Julian Gomez, E. (Principal Investigator), Herrero Abadia, P. (Investigator), Martin Pinardi, L. (Others), Segui Moll, A. (Others) & Torrents Serra, E. (Others)
2/12/24 → 1/06/25
Project: Research Projects and Other Grants
-
PHAGEs_SI: Phage-based solutions to combat Salmonella Infantis in poultry production
Campoy Sanchez, S. (Principal Investigator), Cortes Garmendia, M. P. (Investigator), Llagostera Casas, M. (Investigator), Català Gregori, P. (Others), Conill Bonet, P. (Others), Martin Pinardi, L. (Others), Escribano Fernández, S. (Technician) & Ruiz Sero, J. (Technician)
2/12/24 → 1/06/25
Project: Research Projects and Other Grants
Research output
-
A founder variant in the RYR1 gene is associated with hyperCKemia, myalgia and muscle cramps
Segarra Casas, A., Iruzubieta, P., Kapetanovic, S., Hernández-Laín, A., Jericó, I., Fernández-Torrón, R., Maneiro, M., Marco-Moreno, P., Zelaya-Huerta, M. V., Rodríguez-Santiago, B., Calafell, F., Töpf, A., Straub, V., Vallejo-Illarramendi, A., López de Munain, A., Gallano, P. & Gonzalez-Quereda, L., 1 Jan 2025, In: European Journal of Neurology. 32, 1, 9 p., e16471.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
A Post-Mortem Molecular Damage Profile in the Ancient Human Mitochondrial DNA
Cuesta-Aguirre, D. R., Amor-Jimenez, C., Malgosa, A. & Santos, C., May 2025, In: Molecular Ecology Resources. 25, 4, 12 p., e14061.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Downloads (Pure) -
A Targeted Nanotoxin Inhibits Colorectal Cancer Growth Through Local Tumor Pyroptosis and Eosinophil Infiltration and Degranulation
Carrasco-Díaz, L. M., Gallardo, A., Voltà-Durán, E., Virgili, A. C., Páez, D., Villaverde, A., Vazquez, E., Álamo, P., Unzueta, U., Casanova, I., Mangues, R. & Alba-Castellon, L., 26 Feb 2025, In: International Journal of Nanomedicine. 20, p. 2445-2460 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
Datasets
-
Biological support media influence the bacterial biofouling community in reverse osmosis water reclamation demonstration plants
Ferrera, I. (Creator), Mas, J. (Creator), Taberna, E. (Creator), Sanz, J. (Creator) & Sánchez, O. (Creator), figshare, 15 Apr 2015
DOI: 10.6084/m9.figshare.1314894.v2, https://figshare.com/articles/Biological_support_media_influence_the_bacterial_biofouling_community_in_reverse_osmosis_water_reclamation_demonstration_plants/1314894/2
Dataset
-
Supporting material - Evidence for shared ancestry between Actinobacteria and Firmicutes bacteriophages
Erill, I. (Creator), Koert, M. (Creator) & López-Pérez, J. (Creator), Zenodo, 16 Dec 2020
DOI: 10.5281/zenodo.4645746, https://zenodo.org/record/4645746
Dataset
-
Importance of twitching and surface-associated motility in the virulence of Acinetobacter baumannii
Corral Sabado, J. (Creator), Perez Varela, M. (Creator), Sánchez-Osuna, M. (Creator), Cortés, P. (Creator), Barbé, J. (Creator) & Aranda, J. (Creator), 28 Dec 2021
DOI: 10.6084/m9.figshare.16611341.v2, https://tandf.figshare.com/articles/dataset/Importance_of_twitching_and_surface-associated_motility_in_the_virulence_of_i_Acinetobacter_baumannii_i_/16611341/2
Dataset
Student theses
-
Estudio de los factores de patogenicidad en Escherichia coli enterohemorrágica
Frías Domínguez, B. (Author), Mirelis Otero, B. (Director) & Prats Pastor, G. (Director), 8 Nov 1996Student thesis: Doctoral thesis
-
carcinogénesis de los productos derivados de la cloración del agua
Alicia Marsà (Author), Hernandez Bonilla, A. (Director), 15 Sept 2017Student thesis: Others
-
Evaluación genotóxica de diversos subproductos de la cloración del agua de consumo.
Liviac Muñoz, D. M. (Author), Marcos Dauder, R. (Director), 13 Sept 2006Student thesis: Final degree project (TFG)