Additional file 5: Figure S2. of Depletion of yeast PDK1 orthologs triggers a stress-like transcriptional response

Transcription factors mainly affected by depletion of Pkh. A: Transcription factors mainly involved in controlling the sets of genes found up- and down-regulated (left and right panel, respectively) when SDP8 were grown in the presence of doxycycline for 8 h. Transcription factors with more than 6 or 5 target genes (for up- and down-regulated, respectively) were selected. Only those with a ration of % of predicted/% of expected targets genes ≥ 3 are represented. B: As in A, but for the sets of genes found up- and down-regulated when cells were incubated with doxycycline for 24. Empty bars represent the % of up-regulated genes; filled bars denote the % of down-regulated genes and striped bars indicate the % of expected genes regulated by each transcription factor. Numbers on the top of empty bars denote the ratios % of up-regulated genes/% of expected number of genes regulated by each transcription factor. Numbers on the top of filled bars indicate the ratio of % of down-regulated genes/% of expected number of genes regulated by each transcription factor. (PPTX 91 kb)