What pulmonologists think about the asthma-COPD overlap syndrome

Marc Miravitlles; Bernardino Alcazar; Francisco Javier Alvarez; Teresa Bazus; Myriam Calle; Ciro Casanova; Carolina Cisneros; Juan P. de-Torres; Luis M. Entrenas; Cristobal Esteban; Patricia Garcia-Sidro; Borja G. Cosio; Arturo Huerta; Milagros Iriberri; Jose Luis Izquierdo; Antoln Lopez-Vina; Jose Luis Lopez-Campos; Eva Martinez-Moragon; Luis Perez de Llano; Miguel Perpina; Jose Antonio Ros; Jose Serrano; Juan Jose Soler-Cataluna; Alfons Torrego; Isabel Urrutia; Vicente Plaza

doi:10.2147/COPD.S88667

What pulmonologists think about the asthma-COPD overlap syndrome

Marc Miravitlles, Bernardino Alcazar, Francisco Javier Alvarez, Teresa Bazus, Myriam Calle, Ciro Casanova, Carolina Cisneros, Juan P. de-Torres, Luis M. Entrenas, Cristobal Esteban, Patricia Garcia-Sidro, Borja G. Cosio, Arturo Huerta, Milagros Iriberri, Jose Luis Izquierdo, Antoln Lopez-Vina, Jose Luis Lopez-Campos, Eva Martinez-Moragon, Luis Perez de Llano, Miguel PerpinaJose Antonio Ros, Jose Serrano, Juan Jose Soler-Cataluna, Alfons Torrego, Isabel Urrutia, Vicente Plaza

Producció científica: Contribució a revista › Article › Recerca › Avaluat per experts

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Resum

Background: Alguns pacients amb MPOC poden compartir característiques de l'asma; això és el que s'anomena síndrome d'asma-MPOC (ACOS). No hi ha criteris universalment acceptats per a ACOS, i la majoria dels tractaments per a l'asma i la MPOC no han estat provats adequadament en aquesta població. Materials i mètodes: Hem realitzat una enquesta entre especialistes pulmonars en asma i MPOC amb l'objectiu de recollir les seves opinions sobre ACOS i les seves actituds pel que fa a alguns escenaris de casos de pacients amb ACOS. Els participants van respondre un qüestionari estructurat i van assistir a una reunió cara a cara utilitzant la metodologia Metaplan: per discutir diferents aspectes d'ACOS. Resultats: Un total de 26 pulmonòlegs amb una edat mitjana de 49,7 anys va participar en l'enquesta (13 especialistes en asma i 13 en MPOC). Entre aquests, el 84,6% va reconèixer l'existència d'ACOS i va declarar que un promig del 12,6% dels seus pacients podria tenir aquesta síndrome. A més a més, el 80,8% va acordar que els criteris diagnòstics per ACOS encara no estan ben definits. Les característiques de l'ACOS esmentades amb més freqüència van ser un historial d'asma (88,5%), una exposició significativa al tabaquisme (73,1%) i un volum expiratori forçat en 1 segon/capacitat vital forçada de 0,7 (69,2%). Els criteris diagnòstics més acceptats foren eosinofília a l'esput (80,8%), una prova molt positiva d'un broncodilatador (69,2%) i un historial d'asma abans dels 40 anys d'edat (65,4%). Fins al 96,2% va acordar que el tractament de primera línia per ACOS era la combinació d'un agonista beta(2)-agonista d'acció prolongada/corticosteroides inhalats amb un agent antimuscarínic d'acció prolongada (triple teràpia) per a casos greus d'ACOS. Conclusió: La majoria dels especialistes espanyols en asma i MPOC estan d'acord que l'ACOS existeix, però els criteris diagnòstics encara no estan ben definits. Un historial previ d'asma, tabaquisme i una limitació del flux aeri forçat reversible no són les principals característiques de l'ACOS, amb el tractament de primera línia més acceptat sent un agonista beta(2)-agonista/corticosteroides inhalats d'acció prolongada.

Idioma original	Anglès
Pàgines (de-a)	1321-1330
Nombre de pàgines	10
Revista	International journal of COPD
Volum	10
DOIs	https://doi.org/10.2147/COPD.S88667
Estat de la publicació	Publicada - 2015

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Acos
Copd
Asthma
Guidelines
Survey

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10.2147/COPD.S88667

https://ddd.uab.cat/record/185395

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Miravitlles, M., Alcazar, B., Javier Alvarez, F., Bazus, T., Calle, M., Casanova, C., Cisneros, C., de-Torres, J. P., Entrenas, L. M., Esteban, C., Garcia-Sidro, P., Cosio, B. G., Huerta, A., Iriberri, M., Luis Izquierdo, J., Lopez-Vina, A., Luis Lopez-Campos, J., Martinez-Moragon, E., Perez de Llano, L., ... Plaza, V. (2015). What pulmonologists think about the asthma-COPD overlap syndrome. International journal of COPD, 10, 1321-1330. https://doi.org/10.2147/COPD.S88667

@article{3b96ea2155314e12b2bbc6db4200c4db,

title = "What pulmonologists think about the asthma-COPD overlap syndrome",

abstract = "Background: Some patients with COPD may share characteristics of asthma; this is the so-called asthma-COPD overlap syndrome (ACOS). There are no universally accepted criteria for ACOS, and most treatments for asthma and COPD have not been adequately tested in this population.Materials and methods: We performed a survey among pulmonology specialists in asthma and COPD aimed at collecting their opinions about ACOS and their attitudes in regard to some case scenarios of ACOS patients. The participants answered a structured questionnaire and attended a face-to-face meeting with the Metaplan methodology to discuss different aspects of ACOS.Results: A total of 26 pulmonologists with a mean age of 49.7 years participated in the survey (13 specialists in asthma and 13 in COPD). Among these, 84.6\% recognized the existence of ACOS and stated that a mean of 12.6\% of their patients might have this syndrome. In addition, 80.8\% agreed that the diagnostic criteria for ACOS are not yet well defined. The most frequently mentioned characteristics of ACOS were a history of asthma (88.5\%), significant smoking exposure (73.1\%), and postbronchodilator forced expiratory volume in 1 second/forced vital capacity,0.7 (69.2\%). The most accepted diagnostic criteria were eosinophilia in sputum (80.8\%), a very positive bronchodilator test (69.2\%), and a history of asthma before 40 years of age (65.4\%). Up to 96.2\% agreed that first-line treatment for ACOS was the combination of a long-acting beta(2)-agonist and inhaled steroid, with a long-acting antimuscarinic agent (triple therapy) for severe ACOS.Conclusion: Most Spanish specialists in asthma and COPD agree that ACOS exists, but the diagnostic criteria are not yet well defined. A previous history of asthma, smoking, and not fully reversible airflow limitation are considered the main characteristics of ACOS, with the most accepted first-line treatment being long-acting beta(2)-agonist/inhaled corticosteroids.",

keywords = "Acos, Copd, Asthma, Guidelines, Survey, Acos, Copd, Asthma, Guidelines, Survey, Acos, Copd, Asthma, Guidelines, Survey",

author = "Marc Miravitlles and Bernardino Alcazar and \{Javier Alvarez\}, Francisco and Teresa Bazus and Myriam Calle and Ciro Casanova and Carolina Cisneros and de-Torres, \{Juan P.\} and Entrenas, \{Luis M.\} and Cristobal Esteban and Patricia Garcia-Sidro and Cosio, \{Borja G.\} and Arturo Huerta and Milagros Iriberri and \{Luis Izquierdo\}, Jose and Antoln Lopez-Vina and \{Luis Lopez-Campos\}, Jose and Eva Martinez-Moragon and \{Perez de Llano\}, Luis and Miguel Perpina and \{Antonio Ros\}, Jose and Jose Serrano and \{Jose Soler-Cataluna\}, Juan and Alfons Torrego and Isabel Urrutia and Vicente Plaza",

year = "2015",

doi = "10.2147/COPD.S88667",

language = "English",

volume = "10",

pages = "1321--1330",

}

Miravitlles, M, Alcazar, B, Javier Alvarez, F, Bazus, T, Calle, M, Casanova, C, Cisneros, C, de-Torres, JP, Entrenas, LM, Esteban, C, Garcia-Sidro, P, Cosio, BG, Huerta, A, Iriberri, M, Luis Izquierdo, J, Lopez-Vina, A, Luis Lopez-Campos, J, Martinez-Moragon, E, Perez de Llano, L, Perpina, M, Antonio Ros, J, Serrano, J, Jose Soler-Cataluna, J, Torrego, A, Urrutia, I & Plaza, V 2015, 'What pulmonologists think about the asthma-COPD overlap syndrome', International journal of COPD, vol. 10, pàg. 1321-1330. https://doi.org/10.2147/COPD.S88667

TY - JOUR

T1 - What pulmonologists think about the asthma-COPD overlap syndrome

AU - Miravitlles, Marc

AU - Alcazar, Bernardino

AU - Javier Alvarez, Francisco

AU - Bazus, Teresa

AU - Calle, Myriam

AU - Casanova, Ciro

AU - Cisneros, Carolina

AU - de-Torres, Juan P.

AU - Entrenas, Luis M.

AU - Esteban, Cristobal

AU - Garcia-Sidro, Patricia

AU - Cosio, Borja G.

AU - Huerta, Arturo

AU - Iriberri, Milagros

AU - Luis Izquierdo, Jose

AU - Lopez-Vina, Antoln

AU - Luis Lopez-Campos, Jose

AU - Martinez-Moragon, Eva

AU - Perez de Llano, Luis

AU - Perpina, Miguel

AU - Antonio Ros, Jose

AU - Serrano, Jose

AU - Jose Soler-Cataluna, Juan

AU - Torrego, Alfons

AU - Urrutia, Isabel

AU - Plaza, Vicente

PY - 2015

Y1 - 2015

N2 - Background: Some patients with COPD may share characteristics of asthma; this is the so-called asthma-COPD overlap syndrome (ACOS). There are no universally accepted criteria for ACOS, and most treatments for asthma and COPD have not been adequately tested in this population.Materials and methods: We performed a survey among pulmonology specialists in asthma and COPD aimed at collecting their opinions about ACOS and their attitudes in regard to some case scenarios of ACOS patients. The participants answered a structured questionnaire and attended a face-to-face meeting with the Metaplan methodology to discuss different aspects of ACOS.Results: A total of 26 pulmonologists with a mean age of 49.7 years participated in the survey (13 specialists in asthma and 13 in COPD). Among these, 84.6% recognized the existence of ACOS and stated that a mean of 12.6% of their patients might have this syndrome. In addition, 80.8% agreed that the diagnostic criteria for ACOS are not yet well defined. The most frequently mentioned characteristics of ACOS were a history of asthma (88.5%), significant smoking exposure (73.1%), and postbronchodilator forced expiratory volume in 1 second/forced vital capacity,0.7 (69.2%). The most accepted diagnostic criteria were eosinophilia in sputum (80.8%), a very positive bronchodilator test (69.2%), and a history of asthma before 40 years of age (65.4%). Up to 96.2% agreed that first-line treatment for ACOS was the combination of a long-acting beta(2)-agonist and inhaled steroid, with a long-acting antimuscarinic agent (triple therapy) for severe ACOS.Conclusion: Most Spanish specialists in asthma and COPD agree that ACOS exists, but the diagnostic criteria are not yet well defined. A previous history of asthma, smoking, and not fully reversible airflow limitation are considered the main characteristics of ACOS, with the most accepted first-line treatment being long-acting beta(2)-agonist/inhaled corticosteroids.

AB - Background: Some patients with COPD may share characteristics of asthma; this is the so-called asthma-COPD overlap syndrome (ACOS). There are no universally accepted criteria for ACOS, and most treatments for asthma and COPD have not been adequately tested in this population.Materials and methods: We performed a survey among pulmonology specialists in asthma and COPD aimed at collecting their opinions about ACOS and their attitudes in regard to some case scenarios of ACOS patients. The participants answered a structured questionnaire and attended a face-to-face meeting with the Metaplan methodology to discuss different aspects of ACOS.Results: A total of 26 pulmonologists with a mean age of 49.7 years participated in the survey (13 specialists in asthma and 13 in COPD). Among these, 84.6% recognized the existence of ACOS and stated that a mean of 12.6% of their patients might have this syndrome. In addition, 80.8% agreed that the diagnostic criteria for ACOS are not yet well defined. The most frequently mentioned characteristics of ACOS were a history of asthma (88.5%), significant smoking exposure (73.1%), and postbronchodilator forced expiratory volume in 1 second/forced vital capacity,0.7 (69.2%). The most accepted diagnostic criteria were eosinophilia in sputum (80.8%), a very positive bronchodilator test (69.2%), and a history of asthma before 40 years of age (65.4%). Up to 96.2% agreed that first-line treatment for ACOS was the combination of a long-acting beta(2)-agonist and inhaled steroid, with a long-acting antimuscarinic agent (triple therapy) for severe ACOS.Conclusion: Most Spanish specialists in asthma and COPD agree that ACOS exists, but the diagnostic criteria are not yet well defined. A previous history of asthma, smoking, and not fully reversible airflow limitation are considered the main characteristics of ACOS, with the most accepted first-line treatment being long-acting beta(2)-agonist/inhaled corticosteroids.

KW - Acos

KW - Copd

KW - Asthma

KW - Guidelines

KW - Survey

KW - Acos

KW - Copd

KW - Asthma

KW - Guidelines

KW - Survey

KW - Acos

KW - Copd

KW - Asthma

KW - Guidelines

KW - Survey

UR - http://www.scopus.com/inward/record.url?eid=2-s2.0-84937564455&partnerID=MN8TOARS

UR - https://www.scopus.com/pages/publications/84937564455

U2 - 10.2147/COPD.S88667

DO - 10.2147/COPD.S88667

M3 - Article

C2 - 26270415

SN - 1176-9106

VL - 10

SP - 1321

EP - 1330

JO - International journal of COPD

JF - International journal of COPD

ER -

What pulmonologists think about the asthma-COPD overlap syndrome

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