Valor del óxido nitrico nasal en el diagnóstico de la discinesia ciliar primaria

R. Busquets Monge, G. Vizmanos Lamotte, S. Gartner, N. Cobos Barroso, S. Liñan Cortós, A. Moreno Galdó*, S. Rovira Amigo, C. Reverte Bover, J. Lloreta Trull

*Autor corresponent d’aquest treball

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4 Cites (Scopus)

Resum

Objective: The aim of this study is to report nasal nitric oxide (nNO) values in children with primary ciliary dyskinesia (PCD) and to compare them with nNO values in healthy children, asthmatic children, children with cystic fibrosis and children with post infectious bronchiectasis. Patients and methods: We determined nNO values in 9 children with PCD, 36 asthmatic children, 31 children with cystic fibrosis, 8 children with post infectious bronchiectasis and 37 healthy children. We compared nNO values between these different conditions and calculated sensitivity and specificity of nNO to diagnose PCD. Results: All children with PCD - except one (nNO 348 ppb) - had nNO values below 112 ppb, mean 88 ppb (95%CI 9.6 - 166). The nNO mean was 898 ppb (95%CI 801-995) in healthy children, 1023 ppb (95%CI 911 - 1137) in asthmatic children, 438 ppb (95%CI 367 -508) in cystic fibrosis children and 361 ppb (95%CI 252 - 470) in children with post infectious bronchiectasis. The mean concentration of nNO was lower (P
Títol traduït de la contribucióValue of nasal nitric oxide in the diagnosis of primary ciliary dyskinesia
Idioma originalEspanyol
Pàgines (de-a)88-93
Nombre de pàgines6
RevistaAnales de Pediatria
Volum73
Número2
DOIs
Estat de la publicacióPublicada - d’ag. 2010

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