Translocaciones cromosómicas en los sarcomas de partes blandas: De la biología molecular a la aplicación clínica

A. Masià; M. Rebull; P. Velasco; A. Almazán-Moga; J. Roma; S. Gallego; J. Sánchez De Toledo

doi:10.1016/j.anpedi.2011.09.007

Translocaciones cromosómicas en los sarcomas de partes blandas: De la biología molecular a la aplicación clínica

A. Masià, M. Rebull, P. Velasco, A. Almazán-Moga, J. Roma, S. Gallego, J. Sánchez De Toledo^*

^*Autor corresponent d’aquest treball

Departament de Pediatria, d’Obstetrícia i Ginecologia i de Medicina Preventiva i Salut Pública

Producció científica: Contribució a revista › Article › Recerca › Avaluat per experts

Resum

Recent advances in the knowledge of the molecular biology of paediatric sarcomas, especially the characterisation of chromosomal translocations associated specifically with particular types of cancer, have established bases for the introduction of new diagnostic tools. This article reviews the main chromosomal translocations associated with paediatric tumours, and summarises their molecular characteristics regarding their oncogenic capabilities, possible usefulness as a differential diagnostic tools and possible correlation with clinical parameters.

Títol traduït de la contribució	Chromosomal translocations in soft tissue sarcomas: From molecular biology to clinical application
Idioma original	Espanyol
Pàgines (de-a)	103.e1-103.e7
Revista	Anales de Pediatria
Volum	76
Número	2
DOIs	https://doi.org/10.1016/j.anpedi.2011.09.007
Estat de la publicació	Publicada - de febr. 2012

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title = "Translocaciones cromos{\'o}micas en los sarcomas de partes blandas: De la biolog{\'i}a molecular a la aplicaci{\'o}n cl{\'i}nica",

abstract = "Recent advances in the knowledge of the molecular biology of paediatric sarcomas, especially the characterisation of chromosomal translocations associated specifically with particular types of cancer, have established bases for the introduction of new diagnostic tools. This article reviews the main chromosomal translocations associated with paediatric tumours, and summarises their molecular characteristics regarding their oncogenic capabilities, possible usefulness as a differential diagnostic tools and possible correlation with clinical parameters.",

keywords = "Molecular diagnosis, Paediatric sarcomas, Chromosomal translocations",

author = "A. Masi{\`a} and M. Rebull and P. Velasco and A. Almaz{\'a}n-Moga and J. Roma and S. Gallego and {De Toledo}, {J. S{\'a}nchez}",

year = "2012",

month = feb,

doi = "10.1016/j.anpedi.2011.09.007",

language = "Espa{\~n}ol",

volume = "76",

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T1 - Translocaciones cromosómicas en los sarcomas de partes blandas

T2 - De la biología molecular a la aplicación clínica

AU - Masià, A.

AU - Rebull, M.

AU - Velasco, P.

AU - Almazán-Moga, A.

AU - Roma, J.

AU - Gallego, S.

AU - De Toledo, J. Sánchez

PY - 2012/2

Y1 - 2012/2

N2 - Recent advances in the knowledge of the molecular biology of paediatric sarcomas, especially the characterisation of chromosomal translocations associated specifically with particular types of cancer, have established bases for the introduction of new diagnostic tools. This article reviews the main chromosomal translocations associated with paediatric tumours, and summarises their molecular characteristics regarding their oncogenic capabilities, possible usefulness as a differential diagnostic tools and possible correlation with clinical parameters.

AB - Recent advances in the knowledge of the molecular biology of paediatric sarcomas, especially the characterisation of chromosomal translocations associated specifically with particular types of cancer, have established bases for the introduction of new diagnostic tools. This article reviews the main chromosomal translocations associated with paediatric tumours, and summarises their molecular characteristics regarding their oncogenic capabilities, possible usefulness as a differential diagnostic tools and possible correlation with clinical parameters.

KW - Molecular diagnosis

KW - Paediatric sarcomas

KW - Chromosomal translocations

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DO - 10.1016/j.anpedi.2011.09.007

M3 - Artículo

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SN - 1695-4033

VL - 76

SP - 103.e1-103.e7

JO - Anales de Pediatria

JF - Anales de Pediatria

IS - 2

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Translocaciones cromosómicas en los sarcomas de partes blandas: De la biología molecular a la aplicación clínica

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