Transcript Diversity of Machado–Joseph Disease Gene (ATXN3) Is Not Directly Determined by SNPs in Exonic or Flanking Intronic Regions

Keyphrases

• Single nucleotide Polymorphism 100%
• Disease Genes 100%
• Transcriptome Diversity 100%
• Exonic 100%
• ATXN3 100%
• Alternative Splicing 80%
• Splicing Signals 40%
• Cis-regulatory Elements 20%
• Regulatory Mechanism 20%
• Information Content 20%
• Genomic DNA (gDNA) 20%
• Exon 20%
• ATXN3 Gene 20%
• Splice Variant 20%
• In Silico Analysis 20%
• Transcript Variants 20%
• Splicing Factor 20%
• Alternative Transcripts 20%
• Protein Isoforms 20%
• Regulatory Motifs 20%
• Cis-element 20%
• Complex Modes 20%
• Pre-mRNA 20%
• Regulation Mode 20%
• Exonic Splicing Enhancer 20%
• Recognition Motif 20%
• Multiple Proteins 20%
• Alternative Splicing Regulation 20%
• Splicing Silencer 20%

Biochemistry, Genetics and Molecular Biology

• Single-Nucleotide Polymorphism 100%
• Alternative Splicing 100%
• Ataxin 3 40%
• Regulatory Sequence 20%
• Isoform 20%
• Protein Isoform 20%
• Allele 20%
• Exon 20%
• Enhancer Region 20%
• Splicing Factor 20%
• Precursor mRNA 20%
• Genomics 20%

Neuroscience

• Alternative Splicing 100%
• Single-Nucleotide Polymorphism 100%
• Ataxin 3 40%
• Splicing Factor 20%
• Precursor mRNA 20%
• Enhancer Region 20%
• Exon 20%
• Isoprotein 20%
• Genomic DNA 20%
• Regulatory Sequence 20%