Totally biological composite aortic stentless valved conduit for aortic root replacement: 10-year experience

Manuel Galiñanes, Ayo Meduoye, Ignacio Ferreira, Andrzej Sosnowski

Producció científica: Contribució a revistaArticleRecercaAvaluat per experts

19 Cites (Scopus)

Resum

Objectives: To retrospectively analyze the clinical outcome of a totally biological composite stentless aortic valved conduit (No-React® BioConduit) implanted using the Bentall procedure over ten years in a single centre.Methods: Between 27/10/99 and 19/01/08, the No-React® BioConduit composite graft was implanted in 67 patients. Data on these patients were collected from the in-hospital database, from patient notes and from questionnaires. A cohort of patients had 2D-echocardiogram with an average of 4.3 ± 0.45 years post-operatively to evaluate valve function, calcification, and the diameter of the conduit.Results: Implantation in 67 patients represented a follow-up of 371.3 patient-year. Males were 60% of the operated population, with a mean age of 67.9 ± 1.3 years (range 34.1-83.8 years), 21 of them below the age of 65. After a mean follow-up of 7.1 ± 0.3 years (range of 2.2-10.5 years), more than 50% of the survivors were in NYHA I/II and more than 60% of the survivors were angina-free (CCS 0). The overall 10-year survival following replacement of the aortic valve and root was 51%. During this period, 88% of patients were free from valved-conduit related complications leading to mortality. Post-operative echocardiography studies showed no evidence of stenosis, dilatation, calcification or thrombosis. Importantly, during the 10-year follow-up period no failures of the valved conduit were reported, suggesting that the tissue of the conduit does not structurally change (histology of one explant showed normal cusp and conduit).Conclusions: The No-React® BioConduit composite stentless aortic valved conduit provides excellent long-term clinical results for aortic root replacement with few prosthesis-related complications in the first post-operative decade. © 2011 Galiñanes et al; licensee BioMed Central Ltd.
Idioma originalAnglès
Número d’article86
RevistaJournal of Cardiothoracic Surgery
Volum6
Número1
DOIs
Estat de la publicacióPublicada - 23 de juny 2011

Fingerprint

Navegar pels temes de recerca de 'Totally biological composite aortic stentless valved conduit for aortic root replacement: 10-year experience'. Junts formen un fingerprint únic.

Com citar-ho