TY - JOUR
T1 - Tolerability and profile of the side effects of bupropion
AU - Fora, Facund
AU - Gálvez-Ortiz, Verónica
AU - Cardoner-Álvarez, Narcis
AU - Crespo-Blanco, Jose M.
AU - Navarro-Odriozola, Victor
AU - Garcia-Parés, Gemma
AU - Pérez-Bianco, Josefina
AU - Sánchez-Pérez, Manel
AU - Roncero, Carlos
PY - 2011/10/1
Y1 - 2011/10/1
N2 - Tolerability and the profile of side effects of bupropion are reviewed based on the current literature with special emphasis on sexual function and body weight. Clear evidence exists that bupropion causes less sexual dysfunction than SSRIs and more limited evidence that bupropion may reverse the secondary sexual effects of the SSRIs. On the other hand, contrasted evidence is found that long-term treatment with SSRI may entail some weight gain, while long term treatment with bupropion may entail mild weight loss. Currently, sufficient scientific evidence does not exist to state that bupropion can reverse SSRI-induced weight gain. The results of the review are compared with the opinion of professionals who manage the drug in the daily clinical practice.
AB - Tolerability and the profile of side effects of bupropion are reviewed based on the current literature with special emphasis on sexual function and body weight. Clear evidence exists that bupropion causes less sexual dysfunction than SSRIs and more limited evidence that bupropion may reverse the secondary sexual effects of the SSRIs. On the other hand, contrasted evidence is found that long-term treatment with SSRI may entail some weight gain, while long term treatment with bupropion may entail mild weight loss. Currently, sufficient scientific evidence does not exist to state that bupropion can reverse SSRI-induced weight gain. The results of the review are compared with the opinion of professionals who manage the drug in the daily clinical practice.
M3 - Review article
SN - 1139-9287
VL - 39
SP - 20
EP - 26
JO - Actas Espanolas de Psiquiatria
JF - Actas Espanolas de Psiquiatria
IS - SUPPL. 2
ER -