TY - JOUR
T1 - Therapeutic management and comorbidities in opiate-dependent patients undergoing a replacement therapy programme in Spain: The PROTEUS study
AU - Roncero, Carlos
AU - Fuste, Gideoni
AU - Barral, Carmen
AU - Rodríguez-Cintas, Laia
AU - Martínez-Luna, Nieves
AU - Eiroa-Orosa, Francisco José
AU - Casas, Miguel
PY - 2011/9/1
Y1 - 2011/9/1
N2 - © 2011, Pacini Editore S.p.A. All rights reserved. The aim of this study was to comprehensively describe the clinical comorbidities, concomitant treatments and the current therapeutic management of opiate-dependent patients undergoing a replacement therapy programme (RTP). This is an observational, cross-sectional, multicentre, epidemiological study conducted in 74 healthcare centres for drug users. Patients were diagnosed with Opiate Dependence (OD), and enrolled in a RTP in Spain (N=624). Most patients were men (84%); they received methadone (94%) at a mean dose of 61.52mg/day during the maintenance phase, orally (95%) with take-home doses (76%). High rates of infectious (59%) and psychiatric comorbidities (67%) were found. Patients infected by HIV, HCV or coinfected by HIV/HCV were given significantly higher methadone doses (p<0.0001).
AB - © 2011, Pacini Editore S.p.A. All rights reserved. The aim of this study was to comprehensively describe the clinical comorbidities, concomitant treatments and the current therapeutic management of opiate-dependent patients undergoing a replacement therapy programme (RTP). This is an observational, cross-sectional, multicentre, epidemiological study conducted in 74 healthcare centres for drug users. Patients were diagnosed with Opiate Dependence (OD), and enrolled in a RTP in Spain (N=624). Most patients were men (84%); they received methadone (94%) at a mean dose of 61.52mg/day during the maintenance phase, orally (95%) with take-home doses (76%). High rates of infectious (59%) and psychiatric comorbidities (67%) were found. Patients infected by HIV, HCV or coinfected by HIV/HCV were given significantly higher methadone doses (p<0.0001).
KW - Infectious comorbidites
KW - Opiate dependence
KW - Psychiatric comorbidities
KW - Replacement therapies
KW - Therapeutic management
M3 - Article
SN - 1592-1638
VL - 13
SP - 5
EP - 16
JO - Heroin Addiction and Related Clinical Problems
JF - Heroin Addiction and Related Clinical Problems
IS - 3
ER -
