TY - JOUR
T1 - Theophylline reverses haloperidol-induced catalepsy in the rat possible relevance to the pharmacological treatment of psychosis
AU - Casas, Miquel
AU - Ferre, Sergi
AU - Guix, Teresa
AU - Jane, Francesc
PY - 1988/1/1
Y1 - 1988/1/1
N2 - The effect of theophylline (5, 15, or 30 mg/kg sc) on the catalepsy induced by haloperidol in the rat was studied. Theophylline was shown to induce a dose-dependent inhibition of this catalepsy. These data support the hypothesis that the methylxanthines are dopamine agonists and suggest that coffee, tea, and cola drinks should be avoided by patients undergoing neuroleptic treatment. © 1988.
AB - The effect of theophylline (5, 15, or 30 mg/kg sc) on the catalepsy induced by haloperidol in the rat was studied. Theophylline was shown to induce a dose-dependent inhibition of this catalepsy. These data support the hypothesis that the methylxanthines are dopamine agonists and suggest that coffee, tea, and cola drinks should be avoided by patients undergoing neuroleptic treatment. © 1988.
UR - https://www.scopus.com/pages/publications/0023693963
U2 - 10.1016/0006-3223(88)90138-2
DO - 10.1016/0006-3223(88)90138-2
M3 - Article
SN - 0006-3223
VL - 24
SP - 642
EP - 648
JO - Biological Psychiatry
JF - Biological Psychiatry
IS - 6
ER -