TY - JOUR
T1 - The PHQ-PD as a screening tool for panic disorder in the primary care setting in Spain
AU - Muñoz-Navarro, Roger
AU - Cano-Vindel, Antonio
AU - Wood, Cristina Mae
AU - Ruíz-Rodríguez, Paloma
AU - Medrano, Leonardo Adrián
AU - Limonero, Joaquín T.
AU - Tomás-Tomás, Patricia
AU - Gracia-Gracia, Irene
AU - Dongil-Collado, Esperanza
AU - Iruarrizaga, M. Iciar
AU - Moriana, Juan Antonio
AU - Ochando, Francisco Santolaya
AU - Bonet, Antonio Capafons
AU - Castillo, Ma Dolores Gómez
AU - Fuertes, Fernando Chacón
AU - Cabré, Gonzalo Jiménez
AU - Kvedaras, Estefanía Salgado
AU - González, Jorge Perpiñá
AU - Maeso, Carmen Abellán
AU - Rodrigo, Ana Ma Agudo
AU - Uceda, Ma Del Mar Aguilar
AU - Agüero, Laura
AU - Rodriguez-Enríquez, Mónica
AU - Pizà, Ma Rosa
AU - Ramírez, Ignasi
AU - López, Manuel Aires
AU - Sánchez, Ana María Alayeto
AU - Doménech, Dolores Alfonso
AU - Guinot, Vicenta Almonacid
AU - Torres, Sinuhe Alvarado
AU - Gómez, Sonia Álvarez
AU - Arreaza, Luisa Ma Andrés
AU - Kompanietz, Ana María Arnaiz
AU - García, Ma Pilar Arranz
AU - Hidalgo, Eugenia Avelino
AU - Sánchez, Ma José Ávila
AU - Goicoetxea, Josune Barbero
AU - Solís, Manuel Barragán
AU - López, Pilar Barroso
AU - Izquierdo, Sofía Bauer
AU - Torres, Carmen Benavente
AU - Ortega, Pilar Bermejo
AU - Moreno, Greta Borrás
AU - Romero, Alejandro Buendía
AU - Aguado, Carlos Buiza
AU - Moral, José Caballero
AU - Ezpeleta, Nieves Caparrós
AU - Martínez, Alejandro Casado
AU - Rodríguez, Cristina Casado
AU - Ballesteros, Consuelo Castiblanque
AU - Vicente, Francisca Ceinós
AU - Andrés, Patricia Cordero
AU - Alcaraz, Ana Costa
AU - Cara, Isabel De Andrés
AU - Casares, Victoria De La Riva
AU - Gómez, Bárbara Díaz
AU - Manrique, Ma Dolores Domínguez
AU - Llamazares, Soledad Escolar
AU - Zayas, Encarnación Espinosa De Los Monteros
AU - Jiménez, Aurora Fabero
AU - Payeras, Ma Antonia Font
AU - Gómez, Ma Rosa Fraile
AU - Forteza, Mariona Fuster
AU - Aliu, Montserrat Gallart
AU - Jaén, Olvido García
AU - Palacios, Carmen García
AU - García-Moreno, Mar
AU - Cascales, Yolanda Garnica
AU - Vera, Miguel Gárriz
AU - Martín-Sonseca, Ma Concepción Gómez
AU - Rodríguez, Ma Francisca Gómez
AU - Bosch, César González Blanch
AU - Pasamar, Ana Ma Hermosilla
AU - De Hita, Fernando Hernández
AU - Delgado, Margarita Herrero
AU - Moreno, Josefa Jaimez
AU - Larrabeiti, Amale Jáuregui
AU - Luque, Juan Agustín Jiménez
AU - Moreno, Antonio Jiménez
AU - Dugo, Antonio León
AU - De La Quintana, Carlos Lillo
AU - García, Joaquim L.Limonero
AU - De Frutos, María Lleras
AU - Mestre, Anna Llorca
AU - Ortiz, Francisco López
AU - Moreno, Lourdes Luceño
AU - Almoguera, Pilar Madrid
AU - De La Sierra Fuentes, Sonia Martín
AU - Bustos, Rebeca Martínez
AU - Mullor, Ainoa Mateu
AU - Caballero, Mercedes Matilla
AU - Reyes, Rafael Medina
AU - Gallestegui, Itsaso Mendizábal
AU - Martín, Susana Merino
AU - Vicente, Gonzalo David Moneva
AU - Villa, Ma Isabel Montejo
AU - Cantero, Antonio Montero
AU - Fernández, Julio Montoya
AU - Moreno, Rosario Morales
AU - Hernández, Laura Morante
PY - 2016/8/1
Y1 - 2016/8/1
N2 - © 2016 Muñoz-Navarro et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Introduction Panic disorder is a common anxiety disorder and is highly prevalent in Spanish primary care centres. The use of validated tools can improve the detection of panic disorder in primary care populations, thus enabling referral for specialized treatment. The aim of this study is to determine the accuracy of the Patient Health Questionnaire-Panic Disorder (PHQ-PD) as a screening and diagnostic tool for panic disorder in Spanish primary care centres. Method We compared the psychometric properties of the PHQ-PD to the reference standard, the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) interview. General practitioners referred 178 patients who completed the entire PHQ test, including the PHQ-PD, to undergo the SCID-I. The sensitivity, specificity, positive and negative predictive values and positive and negative likelihood ratios of the PHQ-PD were assessed. Results The operating characteristics of the PHQ-PD are moderate. The best cut-off score was 5 (sensitivity .77, specificity .72). Modifications to the questionnaire's algorithms improved test characteristics (sensitivity .77, specificity .72) compared to the original algorithm. The screening question alone yielded the highest sensitivity score (.83). Conclusion Although the modified algorithm of the PHQ-PD only yielded moderate results as a diagnostic test for panic disorder, it was better than the original. Using only the first question of the PHQ-PD showed the best psychometric properties (sensitivity). Based on these findings, we suggest the use of the screening questions for screening purposes and the modified algorithm for diagnostic purposes.
AB - © 2016 Muñoz-Navarro et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Introduction Panic disorder is a common anxiety disorder and is highly prevalent in Spanish primary care centres. The use of validated tools can improve the detection of panic disorder in primary care populations, thus enabling referral for specialized treatment. The aim of this study is to determine the accuracy of the Patient Health Questionnaire-Panic Disorder (PHQ-PD) as a screening and diagnostic tool for panic disorder in Spanish primary care centres. Method We compared the psychometric properties of the PHQ-PD to the reference standard, the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) interview. General practitioners referred 178 patients who completed the entire PHQ test, including the PHQ-PD, to undergo the SCID-I. The sensitivity, specificity, positive and negative predictive values and positive and negative likelihood ratios of the PHQ-PD were assessed. Results The operating characteristics of the PHQ-PD are moderate. The best cut-off score was 5 (sensitivity .77, specificity .72). Modifications to the questionnaire's algorithms improved test characteristics (sensitivity .77, specificity .72) compared to the original algorithm. The screening question alone yielded the highest sensitivity score (.83). Conclusion Although the modified algorithm of the PHQ-PD only yielded moderate results as a diagnostic test for panic disorder, it was better than the original. Using only the first question of the PHQ-PD showed the best psychometric properties (sensitivity). Based on these findings, we suggest the use of the screening questions for screening purposes and the modified algorithm for diagnostic purposes.
U2 - 10.1371/journal.pone.0161145
DO - 10.1371/journal.pone.0161145
M3 - Article
SN - 1932-6203
VL - 11
JO - PLoS ONE
JF - PLoS ONE
M1 - e0161145
ER -