Synthesis of new N-(4-pyridyl)-1-aminopyrazoles and their muscarinic and adrenergic properties

María Isabel Rodríguez-Franco, Isabel Dorronsoro, Ana Martínez, Concepción Pérez, Albert Badía, Josep E. Baños

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Resum

The synthesis of new N-(4-pyridyl)-1-aminopyrazoles is described. Their binding properties were tested for muscarinic and other neurotransmitter receptors, together with their acetylcholinesterase inhibitory activity. The series derived from 3,5-dimethyl-1H-pyrazole showed moderate activities in both muscarinic and adrenergic receptor binding tests.
Idioma originalAnglès
Pàgines (de-a)118-122
RevistaArchiv der Pharmazie
Volum333
Número5
DOIs
Estat de la publicacióPublicada - 1 de maig 2000

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