Stereoselective Self-Assembly of DNA Binding Helicates Directed by the Viral β-Annulus Trimeric Peptide Motif

Jacobo Gómez-González, David Bouzada, Lidia A. Pérez-Márquez, Giuseppe Sciortino, Jean Didier Maréchal, Miguel Vázquez López*, M. Eugenio Vázquez*

*Autor corresponent d’aquest treball

Producció científica: Contribució a una revistaArticleRecercaAvaluat per experts

3 Cites (Scopus)

Resum

Combining coordination chemistry and peptide engineering offers extraordinary opportunities for developing novel molecular (supra)structures. Here, we demonstrate that the β-annulus motif is capable of directing the stereoselective assembly of designed peptides containing 2,2′-bipyridine ligands into parallel three-stranded chiral peptide helicates, and that these helicates selectively bind with high affinity to three-way DNA junctions.

Idioma originalEnglish
Pàgines (de-a)1564-1569
Nombre de pàgines6
RevistaBioconjugate Chemistry
Volum32
Número8
DOIs
Estat de la publicacióPublicada - 18 d’ag. 2021

Fingerprint

Navegar pels temes de recerca de 'Stereoselective Self-Assembly of DNA Binding Helicates Directed by the Viral β-Annulus Trimeric Peptide Motif'. Junts formen un fingerprint únic.

Com citar-ho