Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines

Xavier Bardina; Jordi Surrallés; Laura Fernández; Elisabet Piñeiro; Antonia Velázquez

Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines

Xavier Bardina, Jordi Surrallés, Laura Fernández, Elisabet Piñeiro, Antonia Velázquez

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The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.

Idioma original	Anglès
Pàgines (de-a)	193-204
Revista	SORT
Volum	30
Número	2
Estat de la publicació	Publicada - 1 de jul. 2006

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title = "Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines",

abstract = "The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.",

keywords = "Inverse regression problem, Confidence interval, Subtoxic concentration",

author = "Xavier Bardina and Jordi Surrall{\'e}s and Laura Fern{\'a}ndez and Elisabet Pi{\~n}eiro and Antonia Vel{\'a}zquez",

year = "2006",

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T1 - Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines

AU - Bardina, Xavier

AU - Surrallés, Jordi

AU - Fernández, Laura

AU - Piñeiro, Elisabet

AU - Velázquez, Antonia

PY - 2006/7/1

Y1 - 2006/7/1

N2 - The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.

AB - The aim of this work is to propose models to study the toxic effect of different concentrations of some standard mutagens in different colon cancer cell lines. We find estimates and, by means of an inverse regression problem, confidence intervals for the subtoxic concentration, that is the concentration that reduces by thirty percent the number of colonies obtained in the absence of mutagen.

KW - Inverse regression problem

KW - Confidence interval

KW - Subtoxic concentration

UR - https://dialnet.unirioja.es/servlet/articulo?codigo=2212588

M3 - Article

SN - 1696-2281

VL - 30

SP - 193

EP - 204

JO - SORT

JF - SORT

IS - 2

ER -

Statistical models to study subtoxic concentrations for some standard mutagens in three colon cancer cell lines

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