Single DNA molecule detection in an optical trap using surface-enhanced Raman scattering

Satish Rao; Saurabh Raj; Stefan Balint; Carlota Bardina Fons; Susana Campoy; Montserrat Llagostera; Dmitri Petrov

doi:10.1063/1.3431628

Single DNA molecule detection in an optical trap using surface-enhanced Raman scattering

Satish Rao, Saurabh Raj, Stefan Balint, Carlota Bardina Fons, Susana Campoy, Montserrat Llagostera, Dmitri Petrov

Departament de Genètica i de Microbiologia

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Raman spectra from single DNA molecules in their natural aqueous environment are presented. A DNA molecule that is anchored between two optically trapped dielectric beads is suspended in a solution with nanosized silver colloid particles. The nonspecific binding of the metal to the DNA enhances the Raman scattering that is excited by a near-infrared beam. A Raman spectrum is first recorded followed by a force-extension curve that verifies the presence of a single DNA molecule. © 2010 American Institute of Physics.

Idioma original	Anglès
Número d’article	213701
Revista	Applied physics letters
Volum	96
DOIs	https://doi.org/10.1063/1.3431628
Estat de la publicació	Publicada - 24 de maig 2010

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10.1063/1.3431628

https://ddd.uab.cat/record/115983

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title = "Single DNA molecule detection in an optical trap using surface-enhanced Raman scattering",

abstract = "Raman spectra from single DNA molecules in their natural aqueous environment are presented. A DNA molecule that is anchored between two optically trapped dielectric beads is suspended in a solution with nanosized silver colloid particles. The nonspecific binding of the metal to the DNA enhances the Raman scattering that is excited by a near-infrared beam. A Raman spectrum is first recorded followed by a force-extension curve that verifies the presence of a single DNA molecule. {\textcopyright} 2010 American Institute of Physics.",

author = "Satish Rao and Saurabh Raj and Stefan Balint and Fons, {Carlota Bardina} and Susana Campoy and Montserrat Llagostera and Dmitri Petrov",

year = "2010",

month = may,

day = "24",

doi = "10.1063/1.3431628",

language = "English",

volume = "96",

journal = "Applied physics letters",

issn = "0003-6951",

publisher = "American Institute of Physics",

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TY - JOUR

T1 - Single DNA molecule detection in an optical trap using surface-enhanced Raman scattering

AU - Rao, Satish

AU - Raj, Saurabh

AU - Balint, Stefan

AU - Fons, Carlota Bardina

AU - Campoy, Susana

AU - Llagostera, Montserrat

AU - Petrov, Dmitri

PY - 2010/5/24

Y1 - 2010/5/24

N2 - Raman spectra from single DNA molecules in their natural aqueous environment are presented. A DNA molecule that is anchored between two optically trapped dielectric beads is suspended in a solution with nanosized silver colloid particles. The nonspecific binding of the metal to the DNA enhances the Raman scattering that is excited by a near-infrared beam. A Raman spectrum is first recorded followed by a force-extension curve that verifies the presence of a single DNA molecule. © 2010 American Institute of Physics.

AB - Raman spectra from single DNA molecules in their natural aqueous environment are presented. A DNA molecule that is anchored between two optically trapped dielectric beads is suspended in a solution with nanosized silver colloid particles. The nonspecific binding of the metal to the DNA enhances the Raman scattering that is excited by a near-infrared beam. A Raman spectrum is first recorded followed by a force-extension curve that verifies the presence of a single DNA molecule. © 2010 American Institute of Physics.

U2 - 10.1063/1.3431628

DO - 10.1063/1.3431628

M3 - Article

SN - 0003-6951

VL - 96

JO - Applied physics letters

JF - Applied physics letters

M1 - 213701

ER -

Single DNA molecule detection in an optical trap using surface-enhanced Raman scattering

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