Sequence of the signal peptide for rat liver mitochondrial aldehyde dehydrogenase

Jaume Farrés; Kun Liang Guan; Henry Weiner

doi:10.1016/0006-291X(88)90740-1

Sequence of the signal peptide for rat liver mitochondrial aldehyde dehydrogenase

Jaume Farrés^*, Kun Liang Guan, Henry Weiner

^*Autor corresponent d’aquest treball

Departament de Bioquímica i de Biologia Molecular

Purdue University

Producció científica: Contribució a revista › Article › Recerca › Avaluat per experts

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The cDNA coding for the signal peptide of rat liver mitochondrial aldehyde dehydrogenase was sequenced. The deduced amino acid sequence of the signal peptide was MIRAALSTARRGPRLSRLL. From this sequence an amphiphilic helix which had a high hydrophobic moment could be constructed. A comparison to the published cDNA sequence of human mitochondrial aldehyde dehydrogenase revealed great sequence identity and allowed us to make some predictions regarding the primary structure of the human signal peptide

Idioma original	Anglès
Pàgines (de-a)	1083-1087
Nombre de pàgines	5
Revista	Biochemical and biophysical research communications
Volum	150
Número	3
DOIs	https://doi.org/10.1016/0006-291X(88)90740-1
Estat de la publicació	Publicada - 15 de febr. 1988

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@article{d2a0139f894f4e9992fb85accddcb550,

title = "Sequence of the signal peptide for rat liver mitochondrial aldehyde dehydrogenase",

abstract = "The cDNA coding for the signal peptide of rat liver mitochondrial aldehyde dehydrogenase was sequenced. The deduced amino acid sequence of the signal peptide was MIRAALSTARRGPRLSRLL. From this sequence an amphiphilic helix which had a high hydrophobic moment could be constructed. A comparison to the published cDNA sequence of human mitochondrial aldehyde dehydrogenase revealed great sequence identity and allowed us to make some predictions regarding the primary structure of the human signal peptide.",

keywords = "Aldehyde Dehydrogenase, Animal, Base Sequence, Comparative Study, DNA, Human, Mitochondria, Liver, Molecular Sequence Data, Protein Conformation, Protein Sorting Signals, Rats, Support, U.S. Gov't, P.H.S.",

author = "Jaume Farr{\'e}s and Guan, \{Kun Liang\} and Henry Weiner",

year = "1988",

month = feb,

day = "15",

doi = "10.1016/0006-291X(88)90740-1",

language = "English",

volume = "150",

pages = "1083--1087",

journal = "Biochemical and biophysical research communications",

issn = "0006-291X",

publisher = "Elsevier",

number = "3",

}

TY - JOUR

T1 - Sequence of the signal peptide for rat liver mitochondrial aldehyde dehydrogenase

AU - Farrés, Jaume

AU - Guan, Kun Liang

AU - Weiner, Henry

PY - 1988/2/15

Y1 - 1988/2/15

N2 - The cDNA coding for the signal peptide of rat liver mitochondrial aldehyde dehydrogenase was sequenced. The deduced amino acid sequence of the signal peptide was MIRAALSTARRGPRLSRLL. From this sequence an amphiphilic helix which had a high hydrophobic moment could be constructed. A comparison to the published cDNA sequence of human mitochondrial aldehyde dehydrogenase revealed great sequence identity and allowed us to make some predictions regarding the primary structure of the human signal peptide.

AB - The cDNA coding for the signal peptide of rat liver mitochondrial aldehyde dehydrogenase was sequenced. The deduced amino acid sequence of the signal peptide was MIRAALSTARRGPRLSRLL. From this sequence an amphiphilic helix which had a high hydrophobic moment could be constructed. A comparison to the published cDNA sequence of human mitochondrial aldehyde dehydrogenase revealed great sequence identity and allowed us to make some predictions regarding the primary structure of the human signal peptide.

KW - Aldehyde Dehydrogenase

KW - Animal

KW - Base Sequence

KW - Comparative Study

KW - DNA

KW - Human

KW - Mitochondria

KW - Liver

KW - Molecular Sequence Data

KW - Protein Conformation

KW - Protein Sorting Signals

KW - Rats

KW - Support

KW - U.S. Gov't

KW - P.H.S.

UR - https://www.scopus.com/pages/publications/0023872823

U2 - 10.1016/0006-291X(88)90740-1

DO - 10.1016/0006-291X(88)90740-1

M3 - Article

C2 - 3342060

AN - SCOPUS:0023872823

SN - 0006-291X

VL - 150

SP - 1083

EP - 1087

JO - Biochemical and biophysical research communications

JF - Biochemical and biophysical research communications

IS - 3

ER -

Sequence of the signal peptide for rat liver mitochondrial aldehyde dehydrogenase

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