Semisynthetic peptide–lipase conjugates for improved biotransformations

Oscar Romero; Marco Filice; Blanca de las Rivas; Cesar Carrasco-Lopez; Javier Klett; Antonio Morreale; Juan A. Hermoso; Jose M. Guisan; Olga Abian; Jose M. Palomo

doi:10.1039/c2cc34816k

Semisynthetic peptide–lipase conjugates for improved biotransformations

Oscar Romero, Marco Filice, Blanca de las Rivas, Cesar Carrasco-Lopez, Javier Klett, Antonio Morreale, Juan A. Hermoso, Jose M. Guisan, Olga Abian, Jose M. Palomo^*

^*Autor corresponent d’aquest treball

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An efficient chemoselective method for the creation of semisynthetic lipases by site-specific incorporation of tailor-made peptides on the lipase-lid site was developed. These new enzymes showed excellent improved specificity and regio- or enantioselectivity in different biotransformations.

Idioma original	Anglès
Pàgines (de-a)	9053-9055
Nombre de pàgines	3
Revista	Chemical Communications
Volum	48
Número	72
DOIs	https://doi.org/10.1039/c2cc34816k
Estat de la publicació	Publicada - 13 d’ag. 2012

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@article{192444b2e48b4600a24ea5b642bc0cfa,

title = "Semisynthetic peptide–lipase conjugates for improved biotransformations",

abstract = "An efficient chemoselective method for the creation of semisynthetic lipases by site-specific incorporation of tailor-made peptides on the lipase-lid site was developed. These new enzymes showed excellent improved specificity and regio- or enantioselectivity in different biotransformations.",

author = "Oscar Romero and Marco Filice and {de las Rivas}, Blanca and Cesar Carrasco-Lopez and Javier Klett and Antonio Morreale and Hermoso, {Juan A.} and Guisan, {Jose M.} and Olga Abian and Palomo, {Jose M.}",

year = "2012",

month = aug,

day = "13",

doi = "10.1039/c2cc34816k",

language = "English",

volume = "48",

pages = "9053--9055",

number = "72",

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TY - JOUR

T1 - Semisynthetic peptide–lipase conjugates for improved biotransformations

AU - Romero, Oscar

AU - Filice, Marco

AU - de las Rivas, Blanca

AU - Carrasco-Lopez, Cesar

AU - Klett, Javier

AU - Morreale, Antonio

AU - Hermoso, Juan A.

AU - Guisan, Jose M.

AU - Abian, Olga

AU - Palomo, Jose M.

PY - 2012/8/13

Y1 - 2012/8/13

N2 - An efficient chemoselective method for the creation of semisynthetic lipases by site-specific incorporation of tailor-made peptides on the lipase-lid site was developed. These new enzymes showed excellent improved specificity and regio- or enantioselectivity in different biotransformations.

AB - An efficient chemoselective method for the creation of semisynthetic lipases by site-specific incorporation of tailor-made peptides on the lipase-lid site was developed. These new enzymes showed excellent improved specificity and regio- or enantioselectivity in different biotransformations.

UR - http://www.scopus.com/inward/record.url?scp=84865005832&partnerID=8YFLogxK

U2 - 10.1039/c2cc34816k

DO - 10.1039/c2cc34816k

M3 - Article

C2 - 22858661

AN - SCOPUS:84865005832

SN - 1359-7345

VL - 48

SP - 9053

EP - 9055

JO - Chemical Communications

JF - Chemical Communications

IS - 72

ER -

Semisynthetic peptide–lipase conjugates for improved biotransformations

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