Safety and Efficacy of Antimicrobial Peptides against Naturally Acquired Leishmaniasis

J. Alberola; A. Rodríguez; O. Francino; X. Roura; L. Rivas; D. Andreu

doi:10.1128/AAC.48.2.641-643.2004

Safety and Efficacy of Antimicrobial Peptides against Naturally Acquired Leishmaniasis

J. Alberola, A. Rodríguez, O. Francino, X. Roura, L. Rivas, D. Andreu

Departament de Farmacologia, de Terapèutica i de Toxicologia

Producció científica: Contribució a revista › Article › Recerca › Avaluat per experts

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Resum

Leishmaniases, which are important causes of morbidity and mortality in humans and dogs, are extremely difficult to treat. Antimicrobial peptides are rarely used as alternative treatments for naturally acquired parasitic diseases. Here we report that the acylated synthetic antimicrobial peptide Oct-CA(1-7)M(2-9) is safe and effective for treating naturally acquired canine leishmaniasis.

Idioma original	Anglès
Pàgines (de-a)	641-643
Revista	Antimicrobial Agents and Chemotherapy
Volum	48
DOIs	https://doi.org/10.1128/AAC.48.2.641-643.2004
Estat de la publicació	Publicada - 1 de febr. 2004

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10.1128/AAC.48.2.641-643.2004

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title = "Safety and Efficacy of Antimicrobial Peptides against Naturally Acquired Leishmaniasis",

abstract = "Leishmaniases, which are important causes of morbidity and mortality in humans and dogs, are extremely difficult to treat. Antimicrobial peptides are rarely used as alternative treatments for naturally acquired parasitic diseases. Here we report that the acylated synthetic antimicrobial peptide Oct-CA(1-7)M(2-9) is safe and effective for treating naturally acquired canine leishmaniasis.",

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T1 - Safety and Efficacy of Antimicrobial Peptides against Naturally Acquired Leishmaniasis

AU - Alberola, J.

AU - Rodríguez, A.

AU - Francino, O.

AU - Roura, X.

AU - Rivas, L.

AU - Andreu, D.

PY - 2004/2/1

Y1 - 2004/2/1

N2 - Leishmaniases, which are important causes of morbidity and mortality in humans and dogs, are extremely difficult to treat. Antimicrobial peptides are rarely used as alternative treatments for naturally acquired parasitic diseases. Here we report that the acylated synthetic antimicrobial peptide Oct-CA(1-7)M(2-9) is safe and effective for treating naturally acquired canine leishmaniasis.

AB - Leishmaniases, which are important causes of morbidity and mortality in humans and dogs, are extremely difficult to treat. Antimicrobial peptides are rarely used as alternative treatments for naturally acquired parasitic diseases. Here we report that the acylated synthetic antimicrobial peptide Oct-CA(1-7)M(2-9) is safe and effective for treating naturally acquired canine leishmaniasis.

UR - https://www.scopus.com/pages/publications/0942301299

U2 - 10.1128/AAC.48.2.641-643.2004

DO - 10.1128/AAC.48.2.641-643.2004

M3 - Article

SN - 0066-4804

VL - 48

SP - 641

EP - 643

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

ER -

Safety and Efficacy of Antimicrobial Peptides against Naturally Acquired Leishmaniasis

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