Reversal of pathology in the entire brain of mucopolysaccharidosis type VII mice after lentivirus-mediated gene transfer

Keyphrases

• Lysosomal Storage Disease 100%
• Mucopolysaccharidosis VII 100%
• Gene Transfer 100%
• Lentivirus 100%
• Multiple Injections 66%
• Storage Lesion 66%
• Brain Injury 33%
• Glia 33%
• Cerebellum 33%
• Enzyme Activity 33%
• Old Animals 33%
• Human Immunodeficiency Virus Type 1 (HIV-1) 33%
• Intracerebral Injection 33%
• Cerebral Hemispheres 33%
• Neurological Symptoms 33%
• Intrastriatal 33%
• β-glucuronidase 33%
• Reporter Gene 33%
• Positive Area 33%
• Serial Sections 33%
• Long-term Expression 33%
• Gene Transfer Vector 33%
• Histochemical Staining 33%
• Perivascular Cells 33%
• Non-dividing Cells 33%
• Local Tolerance 33%
• Disease Regression 33%
• Enzyme Delivery 33%

Neuroscience

• Gene Delivery 100%
• Gene Transfer 100%
• Human Immunodeficiency Virus 100%
• Staining Technique 33%
• Cerebellum 33%
• Beta-Glucuronidase 33%
• Glia 33%
• Enzyme Activity 33%
• Reporter Gene 33%
• Shuttle Vector 33%