TY - JOUR
T1 - Raynaud's phenomenon
AU - Tolosa Vilella, Carles
AU - Simeón Aznar, Carmen Pilar
AU - Gabarró Juli, Lourdes
PY - 2009/5/16
Y1 - 2009/5/16
N2 - Raynauds phenomenon is a frequent reason forseeking of medicalattention, since it affects 35% of the population. It is characterized by sudden, transient and recurrent episodes of pallor and/or digital cyanosis, after exposure to cold or stressful situations. No known underlying illness is identified in over 80% of cases and consequently these cases are classified as primary Raynauds phenomenon. Connective tissue diseases, particularly systemic sclerosis, are the main causes of thephenomenon. Once a complete clinical and physical evaluation rule out other causes, a nailfold capillaroscopy and antinuclear antibodies determination are the most useful adjunctive tests. Mild Raynauds phenomenon can be managed almost exclusively with conservative non-pharmacological lifestyle modifications. However, if a patient develops a severe vascular condition a suitable vasodilator treatment is needed. When critical digital ischemia develops, intravenous treatment with prostaglandin analogues and surgery may be usefu. © 2008 Elsevier Españ a, S.L. All rights reserved.
AB - Raynauds phenomenon is a frequent reason forseeking of medicalattention, since it affects 35% of the population. It is characterized by sudden, transient and recurrent episodes of pallor and/or digital cyanosis, after exposure to cold or stressful situations. No known underlying illness is identified in over 80% of cases and consequently these cases are classified as primary Raynauds phenomenon. Connective tissue diseases, particularly systemic sclerosis, are the main causes of thephenomenon. Once a complete clinical and physical evaluation rule out other causes, a nailfold capillaroscopy and antinuclear antibodies determination are the most useful adjunctive tests. Mild Raynauds phenomenon can be managed almost exclusively with conservative non-pharmacological lifestyle modifications. However, if a patient develops a severe vascular condition a suitable vasodilator treatment is needed. When critical digital ischemia develops, intravenous treatment with prostaglandin analogues and surgery may be usefu. © 2008 Elsevier Españ a, S.L. All rights reserved.
KW - Antinuclear antibodies
KW - Capillaroscopy
KW - Diagnosis
KW - Raynaud's phenomenon
KW - Treatment
U2 - 10.1016/j.medcli.2008.11.017
DO - 10.1016/j.medcli.2008.11.017
M3 - Review article
SN - 0025-7753
VL - 132
SP - 712
EP - 718
JO - Medicina Clinica
JF - Medicina Clinica
IS - 18
ER -