TY - JOUR
T1 - Ratio of T1-weighted to T2-weighted signal intensity as a measure of tissue integrity
T2 - Comparison with magnetization transfer ratio in patients with multiple sclerosis
AU - Pareto, D.
AU - Garcia-Vidal, A.
AU - Alberich, M.
AU - Auger, C.
AU - Montalban, X.
AU - Tintoré, M.
AU - Sastre-Garriga, J.
AU - Rovira,
N1 - Publisher Copyright:
© 2020 American Society of Neuroradiology. All rights reserved.
PY - 2020/3/1
Y1 - 2020/3/1
N2 - The study aim was to compare the ratio of T1WI to T2WI signal intensity (T1/T2) with magnetization transfer ratio, a marker of myelin integrity, in patients with multiple sclerosis. A moderate correlation (r = 0.50, P= .034) was found between the magnetization transfer ratio and T1/T2 in normal-appearing gray matter, and a strong correlation for normal-appearing white matter (r = 0.63, P= .005) and lesions (r = 0.70, P= .001). Results suggest that besides myelin integrity, other factors may be playing a role in T1/T2 measures.
AB - The study aim was to compare the ratio of T1WI to T2WI signal intensity (T1/T2) with magnetization transfer ratio, a marker of myelin integrity, in patients with multiple sclerosis. A moderate correlation (r = 0.50, P= .034) was found between the magnetization transfer ratio and T1/T2 in normal-appearing gray matter, and a strong correlation for normal-appearing white matter (r = 0.63, P= .005) and lesions (r = 0.70, P= .001). Results suggest that besides myelin integrity, other factors may be playing a role in T1/T2 measures.
UR - https://www.scopus.com/pages/publications/85082098784
U2 - 10.3174/AJNR.A6481
DO - 10.3174/AJNR.A6481
M3 - Article
C2 - 32139431
AN - SCOPUS:85082098784
SN - 0195-6108
VL - 41
SP - 461
EP - 463
JO - American Journal of Neuroradiology
JF - American Journal of Neuroradiology
IS - 3
ER -