TY - JOUR
T1 - Rapid SARS-CoV-2 Inactivation in a Simulated Hospital Room Using a Mobile and Autonomous Robot Emitting Ultraviolet-C Light
AU - Lorca-Oró, C.
AU - Vila, J.
AU - Pleguezuelos, P.
AU - Vergara-Alert, J.
AU - Rodon, J.
AU - Majó, N.
AU - López, S.
AU - Segalés, J.
AU - Saldaña-Buesa, F.
AU - Visa-Boladeras, M.
AU - Veà-Baró, A.
AU - Campistol, J.M.
AU - Abad, X.
PY - 2021/11/20
Y1 - 2021/11/20
N2 - The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since 2019 has made mask-wearing, physical distancing, hygiene, and disinfection complementary measures to control virus transmission. Especially for health facilities, we evaluated the efficacy of an UV-C autonomous robot to inactivate SARS-CoV-2 desiccated on potentially contaminated surfaces. ASSUM (autonomous sanitary sterilization ultraviolet machine) robot was used in an experimental box simulating a hospital intensive care unit room. Desiccated SARS-CoV-2 samples were exposed to UV-C in 2 independent runs of 5, 12, and 20 minutes. Residual virus was eluted from surfaces and viral titration was carried out in Vero E6 cells. ASSUM inactivated SARS-CoV-2 by ≥ 99.91% to ≥ 99.99% titer reduction with 12 minutes or longer of UV-C exposure and onwards and a minimum distance of 100cm between the device and the SARS-CoV-2 desiccated samples. This study demonstrates that ASSUM UV-C device is able to inactivate SARS-CoV-2 within a few minutes.
AB - The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since 2019 has made mask-wearing, physical distancing, hygiene, and disinfection complementary measures to control virus transmission. Especially for health facilities, we evaluated the efficacy of an UV-C autonomous robot to inactivate SARS-CoV-2 desiccated on potentially contaminated surfaces. ASSUM (autonomous sanitary sterilization ultraviolet machine) robot was used in an experimental box simulating a hospital intensive care unit room. Desiccated SARS-CoV-2 samples were exposed to UV-C in 2 independent runs of 5, 12, and 20 minutes. Residual virus was eluted from surfaces and viral titration was carried out in Vero E6 cells. ASSUM inactivated SARS-CoV-2 by ≥ 99.91% to ≥ 99.99% titer reduction with 12 minutes or longer of UV-C exposure and onwards and a minimum distance of 100cm between the device and the SARS-CoV-2 desiccated samples. This study demonstrates that ASSUM UV-C device is able to inactivate SARS-CoV-2 within a few minutes.
KW - SARS-CoV-2 inactivation
KW - UV-C radiation
KW - autonomous robots
KW - exponential viral-load reduction
KW - virus inactivation
UR - http://www.scopus.com/inward/record.url?scp=85124633016&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/bb55a5e5-ea52-345b-a2bd-c221237da9e8/
U2 - 10.1093/infdis/jiab551
DO - 10.1093/infdis/jiab551
M3 - Article
C2 - 34904659
SN - 0022-1899
VL - 225
SP - 587
EP - 592
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - 4
ER -
