Progressive multifocal leukoencephalopathy in a patient with relapsing multiple sclerosis treated with ocrelizumab: A case report

Marc Puig-Casadevall, Gary Álvarez-Bravo, Ana Quiroga Varela, René Robles-Cedeño, Laura Sànchez Cirera, Albert Miguela, Gemma Laguillo, Xavier Montalban, Stephen L Hauser, Lluis Ramió-Torrentà

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Resum

INTRODUCTION: Progressive multifocal leukoencephalopathy is a rare but often fatal complication of some multiple sclerosis treatments. Although it has mainly been associated with natalizumab treatment, its appearance with other immunosuppressive therapies has also been reported.

AIMS: The aim of this case report is to describe the development of progressive multifocal encephalopathy in a patient with relapsing-remitting multiple sclerosis treated with ocrelizumab without previous use of natalizumab.

CONCLUSIONS: A summary of the presentation and disease course is provided, presented in the context of the current literature and likely pathophysiology.

Idioma originalEnglish
Pàgines (de-a)3357-3361
Nombre de pàgines5
RevistaEuropean Journal of Neurology
Volum30
Número10
Data online anticipada24 de jul. 2023
DOIs
Estat de la publicacióPublicada - d’oct. 2023

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