Novel transducers for high-channel-count neuroelectronic recording interfaces

Neuroelectronic interfaces with the nervous system are an essential technology in state-of-the-art neuroscience research aiming to uncover the fundamental working mechanisms of the brain. Progress towards increased spatio-temporal resolution has been tightly linked to the advance of microelectronics technology and novel materials. Translation of these technologies to neuroscience has resulted in multichannel neural probes and acquisition systems enabling the recording of brain signals using thousands of channels. This review provides an overview of state-of-the-art neuroelectronic technologies, with emphasis on recording site architectures which enable the implementation of addressable arrays for high-channel-count neural interfaces. In this field, active transduction mechanisms are gaining importance fueled by novel materials, as they facilitate the implementation of high density addressable arrays.